Search Within
PHR1070
Applied Filters:
Keyword:'PHR1070'
Showing 1-30 of 2709 results for "PHR1070" within Papers
Yuki Moriya et al.
Psychopharmacology, 232(8), 1471-1482 (2014-11-05)
Evidence based on clinical and experimental animal studies indicates that adolescent social deprivation influences alcohol consumption in a sex-dependent manner, perhaps by influencing stress responses. However, the mechanisms underlying the interaction between these phenomena remain to be elucidated. Since the
Georgia Pennarossa et al.
Mechanisms of development, 136, 30-39 (2015-02-24)
Parthenogenetic cells, obtained from in vitro activated mammalian oocytes, display multipolar spindles, chromosome malsegregation and a high incidence of aneuploidy, probably due to the lack of paternal contribution. Despite this, parthenogenetic cells do not show high rates of apoptosis and
János T Padra et al.
Infection and immunity, 82(12), 5235-5245 (2014-10-08)
Aeromonas salmonicida subsp. salmonicida infection, also known as furunculosis disease, is associated with high morbidity and mortality in salmonid aquaculture. The first line of defense the pathogen encounters is the mucus layer, which is predominantly comprised of secreted mucins. Here
Ke Qian et al.
Neurochemical research, 39(7), 1206-1218 (2014-04-03)
Citicoline, a natural compound that functions as an intermediate in the biosynthesis of cell membrane phospholipids, is essential for membrane integrity and repair. It has been reported to protect brain against trauma. This study was designed to investigate the protective
Jesse Hwang et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(52), E5706-E5715 (2014-12-17)
An shRNA-mediated screen of the 48 human nuclear receptor genes identified multiple candidates likely to influence the production of human cytomegalovirus in cultured human fibroblasts, including the estrogen-related receptor α (ERRα), an orphan nuclear receptor. The 50-kDa receptor and a
Young-Tae Ju et al.
Journal of cellular biochemistry, 116(2), 277-286 (2014-09-05)
Heat shock protein 20 (HSP20), which is a member of the small heat shock protein family, is known to participate in many pathological processes, such as asthma, intimal hyperplasia, and insulin resistance. However, the function of HSP20 in cancer development
K Krishnanunni et al.
Journal of food science and technology, 52(5), 2572-2584 (2015-04-22)
The objective of this study is to analyze the chemical composition and volatiles present in two medicinal rice varieties of "karungkuravai" and "mappilai samba" and to investigate their total phenolic content and bio activity. Chemical composition of the rice varieties
Subburayan Karthikeyan et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 70, 274-282 (2015-03-18)
Previously, we reported that the prepared resveratrol (RSV) loaded gelatin nanoparticles (GNPs) possessed enhanced anticancer effect than free RSV in non-small cell lung carcinoma cells and Swiss albino mice. The present study aims to explore the relevant mechanism of cell
Mahesh Mohan et al.
Journal of immunology (Baltimore, Md. : 1950), 194(1), 291-306 (2014-12-03)
Persistent gastrointestinal inflammation, a hallmark of progressive HIV/SIV infection, causes disruption of the gastrointestinal epithelial barrier, microbial translocation, and generalized immune activation/inflammation driving AIDS progression. Apart from protein regulators, recent studies strongly suggest critical roles for microRNAs (miRNAs) in regulating
Yi-Fei Chen et al.
International journal of molecular medicine, 34(6), 1591-1598 (2014-10-17)
The difficulties faced in the effective treatment of ovarian cancer are multifactorial, but are mainly associated with relapse and drug resistance. Cancer stem-like cells have been reported to be an important contributor to these hindering factors. In this study, we
Christopher M Peters et al.
Anesthesiology, 122(4), 895-907 (2015-01-13)
Chronic postsurgical pain, a significant public health problem, occurs in 10 to 50% of patients undergoing major surgery. Acute pain induces endogenous analgesia termed conditioned pain modulation (CPM), and the strength of CPM preoperatively predicts the likelihood of chronic postsurgical
Chris Bath et al.
Molecular vision, 20, 797-803 (2014-06-19)
Attempts to determine the transcriptional profile of discrete subsets of limbal epithelial cells in situ using laser capture microdissection (LCM) face two major challenges. First, the transcriptional profile of cells within a tissue may rapidly change as the tissue is
Judith H Robins et al.
PloS one, 9(5), e98002-e98002 (2014-05-29)
The genus Rattus is highly speciose, the taxonomy is complex, and individuals are often difficult to identify to the species level. Previous studies have demonstrated the usefulness of phylogenetic approaches to identification in Rattus but some species, especially among the
Anna Sankiewicz et al.
Analytical biochemistry, 469, 4-11 (2014-10-15)
We have developed a new method for highly selective determination of the ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1) concentration using a surface plasmon resonance imaging (SPRI) technique and two different biosensors. UCH-L1 was captured from a solution by immobilized specific rabbit
Leila Bagheri et al.
Journal of microencapsulation, 31(7), 636-643 (2014-04-29)
Whey proteins were inter-connected either by the enzyme transglutaminase or citric acid and then desolvated with ethanol to generate particles. Both samples comprised of sub-micron (>300 nm) and nano-scaled (~100 nm) particles based on the hydrodynamic size measurements. Enzyme-induced cross-linking
L Marcellin et al.
Human reproduction (Oxford, England), 30(2), 392-405 (2014-11-30)
Are the fetal membranes of women affected with endometriosis similar to those from disease-free women? Decidua of women with endometriosis is able to generate endometriotic-like lesions in contact with the fetal membranes. Eutopic endometrium of women affected with endometriosis presents
Michael M Chen et al.
American journal of physiology. Gastrointestinal and liver physiology, 307(7), G711-G718 (2014-08-12)
Approximately half of all adult burn patients are intoxicated at the time of their injury and have worse clinical outcomes than those without prior alcohol exposure. This study tested the hypothesis that intoxication alters the gut-liver axis, leading to increased
Guanghui Cui et al.
Medical oncology (Northwood, London, England), 32(4), 124-124 (2015-03-20)
Esophageal cancer (EC) is one of the most aggressive malignancies with a distinctly high incidence and mortality rate. Esophageal squamous cell carcinoma (ESCC) is the major histologic subtype of EC, with 40-70 % of tumors overexpressing the epidermal growth factor receptor
Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation.
Ageliki Tsagaratou et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(32), E3306-E3315 (2014-07-30)
The discovery of Ten Eleven Translocation proteins, enzymes that oxidize 5-methylcytosine (5mC) in DNA, has revealed novel mechanisms for the regulation of DNA methylation. We have mapped 5-hydroxymethylcytosine (5hmC) at different stages of T-cell development in the thymus and T-cell
Rima Ait-Belkacem et al.
mAbs, 6(6), 1385-1393 (2014-12-09)
Bevacizumab induces normalization of abnormal blood vessels, making them less leaky. By binding to vascular endothelial growth factor, it indirectly attacks the vascular tumor mass. The optimal delivery of targeted therapies including monoclonal antibodies or anti-angiogenesis drugs to the target
Saidulu Mattapally et al.
BMC medical genetics, 16, 7-7 (2015-05-01)
Congenital heart diseases (CHDs) usually refer to abnormalities in the structure and/or function of the heart that arise before birth. GATA4 plays an important role in embryonic heart development, hence the aim of this study was to find the association
J Koči et al.
Toxicology in vitro : an international journal published in association with BIBRA, 29(2), 289-298 (2014-12-03)
In vitro models are useful tools to initially assess the toxicological safety hazards of food ingredients. Toxicities of cinnamaldehyde (CINA), cinnamon bark oil, lemongrass oil (LGO), thymol, thyme oil (TO), clove leaf oil, eugenol, ginger root extract (GRE), citric acid
Mohammed Iqbal Hossain et al.
PloS one, 9(5), e97570-e97570 (2014-05-27)
Ischemic stroke is the combinatorial effect of many pathological processes including the loss of energy supplies, excessive intracellular calcium accumulation, oxidative stress, and inflammatory responses. The brain's ability to maintain energy demand through this process involves metabolism of glycogen, which
Gareth Harris et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(28), 9389-9403 (2014-07-11)
Food is critical for survival. Many animals, including the nematode Caenorhabditis elegans, use sensorimotor systems to detect and locate preferred food sources. However, the signaling mechanisms underlying food-choice behaviors are poorly understood. Here, we characterize the molecular signaling that regulates
Abigail E Agoglia et al.
Alcoholism, clinical and experimental research, 39(3), 463-475 (2015-02-24)
Binge alcohol drinking is a particularly risky pattern of alcohol consumption that often precedes alcohol dependence and addiction. The transition from binge alcohol drinking to alcohol addiction likely involves mechanisms of synaptic plasticity and learning in the brain. The mitogen-activated
Rui Xie et al.
Bioresource technology, 186, 106-113 (2015-03-31)
Carbonyl compounds generated in biomass pretreatment hinder the biochemical conversion of biomass hydrolysates to biofuels. A novel approach of detoxifying hydrolysates with amino acids for ethanol production was developed. Among the 20 amino acids assessed for their detoxification efficiency and
Nagananda Gurudev et al.
Biology open, 3(5), 332-341 (2014-04-08)
The apical surface of epithelial cells is often highly specialised to fulfil cell type-specific functions. Many epithelial cells expand their apical surface by forming microvilli, actin-based, finger-like membrane protrusions. The apical surface of Drosophila photoreceptor cells (PRCs) forms tightly packed
Haoming Li et al.
In vitro cellular & developmental biology. Animal, 51(4), 329-335 (2014-12-06)
LIM-homeobox genes play a pivotal function in tissue patterning and differentiation, Lhx8 is a member of LIM-homeobox gene family, and it is selectively expressed in embryonic basal forebrain and is a key factor for the determination of cholinergic cells fate.
Ran Du et al.
PloS one, 9(4), e94480-e94480 (2014-04-17)
The rising demand for bioethanol, the most common alternative to petroleum-derived fuel used worldwide, has encouraged a feedstock shift to non-food crops to reduce the competition for resources between food and energy production. Sweet sorghum has become one of the
G P Lv et al.
Journal of pharmaceutical and biomedical analysis, 109, 105-111 (2015-03-15)
It was shown that different extracts had significant differences in the toxicity of Polygonum multiflorum. In this study, the effect of sample preparation on components and liver toxicity of different extracts from P. multiflorum were determined. Hepatoxic components were discovered
Page 1 of 91