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Showing 1-7 of 7 results for "PZ0179" within Papers
Guangbing Wei et al.
Drug design, development and therapy, 9, 3083-3098 (2015-06-26)
Postoperative intra-abdominal adhesions are common complications after abdominal surgery. The exact molecular mechanisms that are responsible for these complications remain unclear, and there are no effective methods for preventing adhesion formation or reformation. The aim of the study reported here
Sara Triñanes et al.
Journal of chromatography. A, 1420, 35-45 (2015-10-18)
The development and performance evaluation of a method for the simultaneous determination of six pharmaceuticals belonging to the class of non-steroidal anti-inflammatory drugs (NSAIDs) which present high selectivity for the cyclooxygenase (COX)-2 isoform of COX (COXIBs) in environmental waters are
Shuang-Long Li et al.
Drug design, development and therapy, 14, 1117-1125 (2020-03-28)
A method for the simultaneous determination of parecoxib and its metabolite valdecoxib in beagle plasma by UPLC-MS/MS was developed and validated. After the plasma was extracted by acetonitrile precipitation, the analytes were separated on an Acquity UPLC BEH C18 column
Disposition of a specific cyclooxygenase-2 inhibitor, valdecoxib, in human
Yuan JJ, et al.
Drug Metabolism and Disposition, 30(9), 1013-1021 (2002)
Determination of parecoxib and valdecoxib in rat plasma by UPLC-MS/MS and its application to pharmacokinetics studies
Chen M, et al.
BMC Pharmacology & Toxicology, 21, 1-10 (2020)
Melina Schellhorn et al.
Oncotarget, 6(36), 39342-39356 (2015-10-30)
The antitumorigenic mechanism of the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib is still a matter of debate. Using lung cancer cell lines (A549, H460) and metastatic cells derived from a lung cancer patient, the present study investigates the impact of celecoxib
Mari-Pau Mena et al.
Experimental cell research, 324(2), 124-136 (2014-03-25)
The mechanisms controlling the switch between the pro-angiogenic and pro-inflammatory states of endothelial cells are still poorly understood. In this paper, we show that: (a) COX-2 expression induced by VEGF-A is NFAT2-dependent; and (b) the integrin profile in endothelial cells
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