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RAB1096
Keyword:'RAB1096'
Showing 1-10 of 10 results for "RAB1096" within Papers
ELABELA concentration is not decreased in maternal plasma before the onset of preeclampsia.
American journal of obstetrics and gynecology, 220(3), 284-285 (2018-12-24)
Current medical science, 40(4), 671-676 (2020-08-31)
Acute respiratory distress syndrome (ARDS) is associated with a mortality of 45%. Our previous research indicated that anti-vascular endothelial growth factor (VEGF) could maintain the normal structure and function of the respiratory barrier. However, systemic application of VEGF antagonists would
American journal of physiology. Regulatory, integrative and comparative physiology, 318(6), R1047-R1057 (2020-05-07)
Preeclampsia is a spontaneously occurring, pregnancy-specific syndrome that is clinically diagnosed by new onset hypertension and proteinuria. Epidemiological evidence describes an association between a history of preeclampsia and increased risk for cardiovascular disease in later life; however, the mechanism(s) driving
Cancer letters, 495, 66-75 (2020-09-07)
Melanoma, a form of skin cancer, is one of the most common cancers in young men and women. Tumors require angiogenesis to provide oxygen and nutrients for growth. Pro-angiogenic molecules such as VEGF and anti-angiogenic molecules such as sFlt-1 control
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(11), 15222-15235 (2020-09-22)
Insufficient remodeling of uterine arteries causes pregnancy-related diseases, including fetal growth restriction and preeclampsia. In these situations, reduced maternal blood flow in the placenta is thought to be responsible for the persistence of a low oxygen environment throughout pregnancy. We
Scientific reports, 10(1), 19618-19618 (2020-11-14)
Gestational complications, including preeclampsia and gestational diabetes, have long-term adverse consequences for offspring's metabolic and cardiovascular health. A low-grade systemic inflammatory response is likely mediating this. Here, we examine the consequences of LPS-induced gestational inflammation on offspring's health in adulthood.
Proceedings of the National Academy of Sciences of the United States of America, 117(40), 24964-24973 (2020-09-23)
Influenza A virus (IAV) infection during pregnancy causes severe maternal and perinatal complications, despite a lack of vertical transmission of IAV across the placenta. Here, we demonstrate a significant alteration in the maternal vascular landscape that underpins the maternal and
Scientific reports, 9(1), 9565-9565 (2019-07-04)
Preeclampsia is a complication of pregnancy characterised by gestational hypertension, proteinuria and/or end organ disease. The reduced uteroplacental perfusion (RUPP) model, via partial occlusion of the lower abdominal aorta, mimics insufficient placental perfusion as a primary causal characteristic of preeclampsia.
Development (Cambridge, England), 147(11) (2020-05-31)
Although widely used, assisted reproductive technologies (ARTs) are associated with adverse perinatal outcomes. To elucidate their underlying causes, we have conducted a longitudinal analysis of placental development and fetal growth using a mouse model to investigate the effects of individual
Gene therapy, 26(12), 479-490 (2019-09-29)
Adeno-associated virus vectors (rAAV) are currently the most common vehicle used in clinical trials of retinal gene therapy, usually delivered through subretinal injections to target cells of the outer retina. However, targeting the inner retina requires intravitreal injections, a simple
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