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Showing 1-30 of 200 results for "racks" within Papers
Yuancun Qiao et al.
The journal of physical chemistry letters, 6(14), 2755-2760 (2015-08-13)
Negative linear compressibility (NLC) is a relatively uncommon phenomenon and rarely studied in organic systems. Here we provide the direct evidence of the persistent NLC in organic mineral ammonium oxalate monohydrate under high pressure using synchrotron X-ray powder diffraction, Raman
S H Inayat-Hussain et al.
Toxicology letters, 191(2-3), 118-122 (2009-08-25)
Goniothalamin, a styryllactone, has been shown to induce cytotoxicity via apoptosis in several tumor cell lines. In this study, we have examined the potential role of several genes, which were stably transfected into T-cell lines and which regulate apoptosis in
S C Fossey et al.
Mammalian genome : official journal of the International Mammalian Genome Society, 11(10), 919-925 (2000-09-26)
The receptors for activated C-kinase (RACK) family of proteins function as anchors for activated protein kinase C (PKC) isoenzymes. Using a monoclonal antibody to RACK1 in the screening of a human hippocampus cDNA library, we identified a novel member of
Jonathan Q Henry et al.
BMC biology, 18(1), 46-46 (2020-05-06)
One hundred years ago, marine organisms were the dominant systems for the study of developmental biology. The challenges in rearing these organisms outside of a marine setting ultimately contributed to a shift towards work on a smaller number of so-called
Marco Racchi et al.
Aging clinical and experimental research, 18(2), 153-157 (2006-05-17)
The purpose of this study was to evaluate in vitro cytokine production in blood leukocytes obtained from sporadic AD patients, aged controls and young individuals. Diluted whole blood was treated in the presence or absence of LPS (1 microg/mL) for
S H Inayat-Hussain et al.
Toxicology letters, 191(2-3), 118-122 (2009-08-25)
Goniothalamin, a styryllactone, has been shown to induce cytotoxicity via apoptosis in several tumor cell lines. In this study, we have examined the potential role of several genes, which were stably transfected into T-cell lines and which regulate apoptosis in
Hyun-Gyo Lee et al.
Neurotoxicology, 28(2), 408-414 (2006-06-27)
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is known to induce neurotoxic effects. However, the mechanism of TCDD-mediated signaling pathways and its possible molecular targets in neurons remains unknown. In this study, we analyzed effects of TCDD on neurofilament subunits, receptor for activated C kinase-1
Erkang Ai et al.
Molecular biology of the cell, 20(6), 1629-1638 (2009-01-23)
Membrane trafficking pathways are necessary for the addition and removal of membrane during cytokinesis. In animal cells, recycling endosomes act as a major source of the additional membranes during furrow progression and abscission. However, the mechanisms and factors that regulate
Diane A Schwartz et al.
The journal of trauma and acute care surgery, 79(1), 15-21 (2015-06-20)
Health care providers are increasingly focused on cost containment. One potential target for cost containment is in-hospital management of acute cholecystitis. Ensuring cholecystectomy within 24 hours for cholecystitis could mitigate costs associated with longer hospitalizations. We sought to determine the
M Csukai et al.
The Journal of biological chemistry, 272(46), 29200-29206 (1997-11-20)
Distinct subcellular localization of activated protein kinase C (PKC) isozymes is mediated by their binding to isozyme-specific RACKs (receptors for activated C-kinase). Our laboratory has previously isolated one such protein, RACK1, and demonstrated that this protein displays specificity for PKCbeta.
Hee-Young Park et al.
Journal of cell science, 117(Pt 16), 3659-3668 (2004-07-15)
Protein kinase C (PKC), a family of at least eleven isoforms, mediates numerous cell functions. In human melanocytes, alpha, beta, delta, epsilon and zeta isoforms of PKC are expressed, but uniquely PKC-beta activates tyrosinase, the key and the rate-limiting enzyme
Emanuela Corsini et al.
Journal of leukocyte biology, 77(2), 247-256 (2004-11-19)
Aging is associated with remodeling of the immune system, contributing to increased incidence of infections, autoimmune diseases, and cancer among the elderly. Alterations in several signal transduction pathways have been reported to play an important role in immunosenescence. We show
Abhishek Shrivastava et al.
Science advances, 6(10), eaay6616-eaay6616 (2020-03-18)
The gliding bacterium Flavobacterium johnsoniae is known to have an adhesin, SprB, that moves along the cell surface on a spiral track. Following viscous shear, cells can be tethered by the addition of an anti-SprB antibody, causing spinning at 3
Juhyun Han et al.
Molecules and cells, 14(3), 420-424 (2003-01-11)
To isolate and characterize a novel protein that interacts with nuclear factor of activated T cells (NFAT) and potentially regulates its activity, we screened a Jurkat cDNA library by using the NFAT regulatory domain as bait in the yeast two-hybrid
Juan Ramírez et al.
Inorganic chemistry, 48(6), 2456-2463 (2009-03-10)
A novel class of ditopic ligands, 1, was synthesized by the reaction of 2,5-pyrazine-dicarboxaldehyde with 2 equiv of acyl-/aroyl-hydrazine. Their structures were confirmed by 1D and 2D NMR and by X-ray crystallography. They gave heteroleptic Cu(II) dinuclear rack-like complexes of
S A Rotenberg et al.
The Journal of biological chemistry, 273(4), 2390-2395 (1998-01-27)
1,1'-Decamethylenebis-4-aminoquinaldinium diiodide (DECA; dequalinium) is an anti-tumor agent and protein kinase C (PKC) inhibitor whose mechanism of action with PKC is unknown. This study reports that with human PKC alpha, DECA exhibited competitive inhibition (Ki = 11.5 +/- 5 microM)
Shanmugam Marudhupandiyan et al.
Developmental and comparative immunology, 74, 227-236 (2017-05-16)
The nematode C. elegans has the ability to clear off bacterial colonization in the intestine using pathogen specific innate immune response. Here, we show that C. elegans RACK-1 has been vital in determining the survival of worms under specific pathogenic infection. Among
Anna Usacheva et al.
Journal of immunology (Baltimore, Md. : 1950), 171(6), 2989-2994 (2003-09-10)
The WD repeat-containing protein receptor for activated protein kinase C (RACK)-1 has been linked to a variety of signaling systems including protein kinase C, growth factors, and IFNs. In the IFN system, RACK-1 functions as an adaptor recruiting the transcription
Anna Usacheva et al.
Journal of immunology (Baltimore, Md. : 1950), 171(6), 2989-2994 (2003-09-10)
The WD repeat-containing protein receptor for activated protein kinase C (RACK)-1 has been linked to a variety of signaling systems including protein kinase C, growth factors, and IFNs. In the IFN system, RACK-1 functions as an adaptor recruiting the transcription
E Croze et al.
Journal of immunology (Baltimore, Md. : 1950), 165(9), 5127-5132 (2000-10-25)
The cytoplasmic domain of the human type I IFN receptor chain 2 (IFNAR2c or IFN-alphaRbetaL) was used as bait in a yeast two-hybrid system to identify novel proteins interacting with this region of the receptor. We report here a specific
Hamilton et al.
Marine biotechnology (New York, N.Y.), 1(3), 279-285 (1999-06-29)
: We have cloned and sequenced complementary DNAs coding for a receptor for activated C kinase (RACK) from two species of teleost fishes, zebrafish (Danio rerio) and tilapia (Oreochromis niloticus). The tilapia clone is 1063 nucleotides long, and the zebrafish
Shu Wang et al.
Molecular biology reports, 30(1), 53-60 (2003-04-12)
During a large-scale screen of a human fetal brain cDNA library, a novel human gene GNB2L1 encoding a novel RACK (receptor of activated protein kinase C) protein was isolated and sequenced. The cDNA is 1142 bp long and has a
Adrian-Mihail Stadler et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 16(19), 5645-5660 (2010-04-10)
A novel class of polytopic hydrazone-based ligands was synthesized. They gave heteroleptic Ru(II) polynuclear rack-like complexes of formula [Ru(n)terpy(n)(bridging molecular strand)](2n+) (terpy=2,2':6',2''-terpyridine). The new rack-like systems can be viewed as being made of two identical or roughly identical peripheral subunits
Djamila Ouaret et al.
Cell cycle (Georgetown, Tex.), 13(17), 2697-2706 (2014-12-09)
Enzastaurin is a selective inhibitor of protein kinase C β and a potent inhibitor of tumor angiogenesis. In addition, enzastaurin shows direct cytotoxic activity toward a subset of tumor cells including colorectal cancer cells (CRC). In spite of promising results
Djamila Ouaret et al.
Cell cycle (Georgetown, Tex.), 13(17), 2697-2706 (2014-12-09)
Enzastaurin is a selective inhibitor of protein kinase C β and a potent inhibitor of tumor angiogenesis. In addition, enzastaurin shows direct cytotoxic activity toward a subset of tumor cells including colorectal cancer cells (CRC). In spite of promising results
J Rack et al.
Hepato-gastroenterology, 30(6), 258-260 (1983-12-01)
Smoking predisposes to peptic ulcer. Bound N-acetylneuraminic acid (NANA) is an essential constituent of mucus. In order to examine whether smoking changes gastric mucus secretion, the concentration of N-acetylneuraminic acid was measured in the gastric juice of 10 non-smokers and
M Rack
Pflugers Archiv : European journal of physiology, 404(2), 126-130 (1985-05-01)
Voltage clamped single nerve fibres of the frog Rana esculenta were treated with the amino groups specific reagents ethyl acetimidate and isethionyl acetimidate. Ethyl acetimidate is lipid soluble, relatively non-polar and can penetrate a membrane. Isethionyl acetimidate is lipid-insoluble, polar
Effects of chemical modification on Na channel function.
M Rack et al.
Journal of protein chemistry, 8(3), 394-397 (1989-06-01)
Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta
Racke MM, et al.
The Journal of Neuroscience, 25(3), 629-636 (2005)
Rodney Stuart et al.
Journal of neuroimmunology, 191(1-2), 45-50 (2007-10-09)
Several studies have examined whether a dimorphism in the CD152 costimulatory molecule may influence the development of multiple sclerosis (MS). A sample of 108 patients with a diagnosis of relapsing remitting (RRMS), 28 with secondary progressive (SPMS), 23 with primary
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