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Showing 1-30 of 63 results for "S-008" within Papers
J Fechner et al.
European journal of pain (London, England), 17(4), 562-570 (2012-08-29)
There is an ongoing debate whether opioids when used for intra-operative analgesia may enhance post-operative pain. We studied the effect of two different intra-operative dosings of sufentanil on post-operative morphine consumption, pain and hyperalgesia after cardiac anaesthesia. Forty-two male patients
Marc Lilot et al.
Anesthesia and analgesia, 117(1), 259-264 (2013-04-18)
In this randomized, prospective trial, we sought to determine the effective dose of hypobaric ropivacaine with sufentanil providing 95% success (ED95) in spinal anesthesia for traumatic femoral neck surgery in the elderly. Sixty-eight elderly patients with unilateral hip fracture randomly
Xin Wang et al.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 21(5), 1140-1145 (2012-12-12)
To evaluate the effect of combined local anaesthetic and opioid in post-operative analgesia, the effect of intra-articular injection of local anaesthetic (ropivacaine), opioid (sufentanil) and combination of these two (ropivacaine combined with sufentanil) after the single-bundle anterior cruciate ligament reconstruction
Robert Stephen et al.
Journal of opioid management, 8(4), 237-241 (2012-09-04)
In emergency medicine, the ability to provide rapid, adequate pain control without high resource utilization is ideal. In this study, the efficacy of intranasal sufentanil in emergency department (ED) patients with acute distal extremity injury was evaluated. A nonrandomized, open-label
S Karason et al.
Acta anaesthesiologica Scandinavica, 57(5), 639-645 (2013-02-26)
Bladder catheterisation may be inconvenient for patients, delay mobilisation and risk complications. We hypothesised that by excluding pre-operatively patients at high risk of post-operative urinary retention, the majority of patients could avoid perioperative catheterisation during low-dose spinal anaesthesia. Patients undergoing
Jean-Christophe Orban et al.
PloS one, 7(9), e45284-e45284 (2012-10-11)
Cardiac arrest is a major health concern worldwide accounting for 375,000 cases per year in Europe with a survival rate of <10%. Therapeutic hypothermia has been shown to improve patients' neurological outcome and is recommended by scientific societies. Despite these
Chantal Mamie et al.
Anesthesia and analgesia, 116(1), 170-177 (2012-12-12)
There is currently no evidence about the genetic bases of postoperative pain variability in children. We prospectively followed a cohort of 168 children after orthopedic or abdominal surgery, who were under morphine patient-controlled analgesia. The children and their parents were
B A Zanfini et al.
European review for medical and pharmacological sciences, 16(11), 1525-1529 (2012-11-01)
This study evaluates the effects of spinal anesthesia with hyperbaric bupivacaine plus sufentanil on bladder function in women undergoing cesarean section. Thirty caucasian healthy pregnants scheduled for elective Cesarean section under spinal anesthesia performed with hyperbaric bupivacaine plus sufentanil were
J L Manfio et al.
Drug research, 63(10), 495-500 (2013-06-20)
Plasma monitoring and pharmacokinetic assessment are important tools used in therapeutic control. Sufentanil is responsible for the hemodynamic stabilization of patients, providing better suppression of the neuroendocrine response compared to its analogue fentanyl. This study aims to use the plasma
Terry J Kreeger et al.
Journal of wildlife diseases, 48(4), 1088-1091 (2012-10-13)
Free-ranging Alaskan moose calves (Alces alces gigas) were immobilized with 0.12 mg/kg sufentanil (S; n=16), 0.12 mg/kg sufentanil plus 0.27 mg/kg xylazine (SX; n=11), or 0.007 mg/kg carfentanil plus 0.36 mg/kg xylazine (CX; n=13). Immobilants were antagonized with 1.2 mg/kg
Aline Albi-Feldzer et al.
Anesthesiology, 118(2), 318-326 (2013-01-24)
The efficacy of local anesthetic wound infiltration for the treatment of acute and chronic postoperative pain is controversial and there are no detailed studies. The primary objective of this study was to evaluate the influence of ropivacaine wound infiltration on
Intranasal sufentanil and its emerging clinical applications: beyond its role in the emergency department.
Shailendra Kapoor
Journal of opioid management, 8(6), 341-341 (2012-12-25)
Patricia Hedenqvist et al.
BMC veterinary research, 9, 21-21 (2013-01-29)
Anaesthesia in rabbits is associated with a high mortality rate, compared to that in cats and dogs. Total intravenous anaesthesia (TIVA) with drugs that provide cardiovascular stability and are rapidly metabolised could be of benefit for use in rabbits. The
C E Rosow
Pharmacotherapy, 4(1), 11-19 (1984-01-01)
Sufentanil citrate is a potent analogue of fentanyl that has been evaluated primarily for use in opioid anesthesia. It is a pure mu receptor agonist and produces the typical spectrum of opioid effects. The major side effects are truncal rigidity
Jacob Steenblik et al.
The American journal of emergency medicine, 30(9), 1817-1821 (2012-05-29)
Painful extremity injuries are common patient complaints in resort clinics, urgent care clinics, and emergency departments. We hypothesized that intranasal (IN) sufentanil could provide rapid, noninvasive, effective pain relief to patients presenting with acute extremity injuries. This was an unblinded
Case scenario: severe emergence agitation after myringotomy in a 3-yr-old child.
Souhayl Dahmani et al.
Anesthesiology, 117(2), 399-406 (2012-06-23)
T H Lunn et al.
British journal of anaesthesia, 110(1), 66-73 (2012-09-19)
High-dose glucocorticoid may reduce postsurgical pain and improve recovery. We hypothesized that 125 mg methylprednisolone (MP) would reduce time to meet functional discharge criteria after total hip arthroplasty (THA). Forty-eight patients undergoing unilateral THA under spinal anaesthesia were consecutively included
Cristiane Volobuef et al.
Journal of pharmaceutical sciences, 101(10), 3698-3707 (2012-06-28)
Sufentanil (SUF) is a synthetic analgesic opioid widely used for the management of acute and chronic pain. This drug was complexed with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) and the physicochemical characterization, in vitro/ex vivo toxicity assays, and pharmacological evaluation were performed. Differential scanning
Sébastien Grastilleur et al.
Biological chemistry, 394(3), 361-368 (2013-01-18)
Postoperative pain management is a clinical challenge that can be complicated by opioid-induced hyperalgesia (OIH). Kinin receptors could mediate both the acute and chronic phases of inflammation and pain. A few recent studies suggest that dynorphin A could maintain neuropathic
Criteria for use of fentanyl citrate, sufentanil citrate, and alfentanil hydrochloride.
G B Satterlee et al.
Clinical pharmacy, 10(8), 635-637 (1991-08-01)
Xu Lili et al.
Paediatric anaesthesia, 22(12), 1216-1220 (2012-06-21)
Both over- and undercorrection can occur in up to 10-15% of strabismus surgeries. Use of adjustable suture technique and an intraoperative awake test may decrease the incidence of over- or undercorrection. In this study, we investigated the ability to provide
S Dango et al.
British journal of anaesthesia, 110(3), 443-449 (2012-11-16)
Although thoracic epidural analgesia (TEA) is considered the gold standard for post-thoracotomy pain relief, thoracic paravertebral block (PVB) and intrathecal opioid (ITO) administration have also been shown to be efficacious. We hypothesized that the combination of PVB and ITO provides
Shen Sun et al.
Journal of anesthesia, 27(1), 25-28 (2012-08-28)
We aimed to investigate the effects of pretreatment with a small dose of dexmedetomidine on the cough caused by sufentanil during anesthetic induction. Two hundred and forty patients undergoing elective gynecological surgery under general anesthesia were randomly allocated to 4
Ramesh Rajan et al.
The European journal of neuroscience, 37(6), 924-941 (2013-01-03)
Many anaesthetics commonly used in auditory research severely depress cortical responses, particularly in the supragranular layers of the primary auditory cortex and in non-primary areas. This is particularly true when stimuli other than simple tones are presented. Although awake preparations
Jingchuan Wu et al.
Journal of neurochemistry, 153(6), 710-726 (2020-01-18)
The level of microRNA-9-5p (miRNA-9-5p) in brain tissues is significantly changed after traumatic brain injury (TBI). However, the effect of miRNA-9-5p for brain function in TBI has not been elucidated. In this study, a controlled cortical impact model was used
Harold S Minkowitz et al.
Regional anesthesia and pain medicine, 38(2), 131-139 (2012-12-29)
A sublingual sufentanil tablet is being developed as a potential alternative to intravenous (IV) opioids for the management of postoperative pain. The objective of these studies was to evaluate the pharmacokinetics, efficacy, and safety of sublingual sufentanil tablets for postoperative
Christian Jeleazcov et al.
Anesthesiology, 120(2), 378-391 (2013-08-21)
Hydromorphone is a µ-selective opioid agonist used in postoperative pain therapy. This study aimed to evaluate the pharmacokinetics of hydromorphone in cardiac surgery patients during postoperative analgesia with target-controlled infusion and patient-controlled analgesia. In this study, 50 adult patients were
T I Saari et al.
British journal of anaesthesia, 113(4), 677-687 (2014-07-09)
Our objective was to evaluate the effect of intensive care treatment on the protein binding of sufentanil and hydromorphone in cardiac surgery patients during postoperative analgesia using a target-controlled infusion (TCI) and patient-controlled analgesia (PCA). Fifty adult patients were enrolled
C Jeleazcov et al.
British journal of anaesthesia, 109(5), 698-706 (2012-07-27)
Target controlled infusion (TCI) with sufentanil is usually performed using the Gepts model, which was derived from patients undergoing general surgery. It is, however, known that pharmacokinetics of sufentanil can be changed during cardiopulmonary bypass (CPB). We tested whether TCI
Q L Chen et al.
Acta anaesthesiologica Scandinavica, 57(2), 236-242 (2012-08-14)
Sufentanil is widely used in clinical anaesthesia because of its protective effects against ischaemia/reperfusion injury. Diabetes mellitus elevates the activity of glycogen synthase kinase-3β (GSK-3β), thereby increasing the permeability of mitochondrial transition pore. This study investigated the role of GSK-3β
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