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Showing 1-30 of 30 results for "S7010" within Papers
N Realdon et al.
Die Pharmazie, 63(6), 459-463 (2008-07-09)
The addition of surfactants to suppository formulations is referred to in the scientific literature, but their effects on drug availability remain uncertain. Surfactants are reported to improve drug dispersion into hard fatty excipients, to increase the spreading of the melted
Jun-chan Li et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 40(11), 970-975 (2006-02-28)
To study the release and cell uptake characteristics of 9-nitrocamptothecin (9-NC) nanostructured lipid carrier system (NLC) in vitro and its tissue distribution characteristics in vivo. Mouse peritoneal macrophages were used to investigate the uptake of nanoparticles by cells in vitro.
Karimunnisa Sameer Shaikh et al.
Drug development and industrial pharmacy, 36(8), 946-953 (2010-03-04)
Niosomal delivery can prove an alternative to improve the poor skin penetration and residence of the topical antifungal drugs that account for the long treatment regimes in cutaneous mycosis. To investigate niosomes as carriers for dermal delivery of ciclopirox olamine
N Rungphanichkul et al.
Die Pharmazie, 66(8), 570-575 (2011-09-10)
Curcuminoids (curcumin, desmethoxycurcumin, and bisdesmethoxycurcumin) are major bioactive substances found in turmeric (Curcuma longa L.) extracts and possess antioxidant, anti-inflammatory, antimicrobial and anticancer properties. In this study, curcuminoid niosomes prepared with a series of Span non-ionic surfactants were developed to
Mohamed Nasr
AAPS PharmSciTech, 11(1), 85-89 (2010-01-09)
The objectives of this research were to prepare celecoxib proniosomes and evaluate the influence of proniosomal formulation on the oral bioavailability of the drug in human volunteers. A new proniosomal delivery system for a poorly water-soluble drug such as celecoxib
A Manosroi et al.
International journal of pharmaceutics, 356(1-2), 291-299 (2008-02-19)
Characteristics and physical stability of luciferase plasmid (pLuc) entrapped in cationic bilayer vesicles prepared from various molar ratios of amphiphiles (DPPC, Tween61 or Span60), cholesterol (Chol) and cationic charge lipid (DDAB) were investigated. The cationic liposomes were composed of DPPC/Chol/DDAB
F Podczeck et al.
International journal of pharmaceutics, 361(1-2), 33-40 (2008-06-24)
The aim of the study was to investigate the possibility of incorporating non-ionic surfactants into pellets produced from microcrystalline cellulose by the process of extrusion/spheronization and the properties of the pellets. A hydrophilic surfactant, polysorbate 60 (PS 60), and two
I F Uchegbu et al.
Pharmaceutical research, 12(7), 1019-1024 (1995-07-01)
Encapsulation of doxorubicin in niosomes was sought as a route to tumour targeting and improved tumoricidal through the alteration of doxorubicin pharmacokinetics and metabolism. Doxorubicin niosomes (10 mg kg-1 doxorubicin) prepared from sorbitan monostearate (Span 60), cholesterol and choleth-24 (a
I F Almeida et al.
Pharmaceutical development and technology, 13(6), 487-494 (2008-08-23)
The aim of this study was to obtain new vehicles for topical formulations based on the mixture of hydrogels (aqueous systems) with oleogels (lipophilic systems). Several formulations were prepared using different oleogels mixed with polyacrylic acid hydrogel without addition of
Preparation and properties of vesicles (niosomes) of sorbitan monoesters ([TM="Span"] 20, 40, 60 and 80) and a sorbitan triester ([TM="Span"] 85).
Yoshioka, T., et al.
International Journal of Pharmaceutics, 105, 1-1 (1994)
Mona Basha et al.
Journal of liposome research, 23(3), 203-210 (2013-04-24)
The objective of this study was to develop an efficient ocular nanovesicular carrier providing a controlled delivery of Clotrimazole (CLT); a water insoluble antifungal drug. The nanovesicular carriers were formulated using Span 60 with one of the following edge activators
Prasun Bandyopadhyay et al.
Colloids and surfaces. B, Biointerfaces, 58(2), 305-308 (2007-04-07)
A study of the self-organization of nonionic surfactant span 60 (sorbitan mono stearate) in presence of fatty alcohol (stearyl, cetyl and lauryl) is presented. When ethanolic solution of the surfactant-fatty alcohol (1:1) mixture is added in water spontaneous large unilamellar
Isabel F Almeida et al.
International journal of pharmaceutics, 327(1-2), 73-77 (2006-09-26)
Oleogels are semisolid systems obtained with an organogelator and a hydrophobic liquid that have been investigated over the past few years and that could play an important role as dermatological bases. Recently, we have developed an oleogel of sorbitan monostearate
Abdelbary Elhissi et al.
International journal of pharmaceutics, 444(1-2), 193-199 (2013-01-10)
The aerosol properties of niosomes were studied using Aeroneb Pro and Omron MicroAir vibrating-mesh nebulizers and Pari LC Sprint air-jet nebulizer. Proniosomes were prepared by coating sucrose particles with Span 60 (sorbitan monostearate), cholesterol and beclometasone dipropionate (BDP) (1:1:0.1). Nano-sized
Fahima Hashim et al.
Drug delivery, 17(5), 282-287 (2010-03-31)
The objectives of this research were to prepare ribavirin niosomes and evaluate the influence of niosomal encapsulation on drug liver targeting in rats. Ribavirin niosomes were prepared by the thin film hydration method using span 60, cholesterol, and dicetyl phosphate
Aline Ferreira Ourique et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 79(1), 95-101 (2011-03-16)
The aims of this work were to increase the photostability and to reduce the skin permeation of tretinoin through nanoencapsulation. Tretinoin is widely used in the topical treatment of various dermatological diseases such as acne, psoriasis, skin cancer, and photoaging.
Zhanwen Xing et al.
Acta biomaterialia, 6(9), 3542-3549 (2010-03-17)
In this study, novel perfluorocarbon-filled microbubbles as ultrasound contrast agent were fabricated using ultrasonication of a surfactant mixture of sorbitan monostearate (Span 60) and polyoxyethylene 40 stearate (PEG40S) in aqueous media. The microbubbles generated from a 1:9 mixture of PEG40S/Span
Qiangzhong Zhao et al.
Food chemistry, 141(3), 1834-1840 (2013-07-23)
In this work, the effects of sorbitan monostearate (Span 60) level on the particle size distribution, microstructure and apparent viscosity of the emulsion were investigated. Average particle size (d4,3), surface protein concentration, partial coalescence of fat and overrun of whipped
Amit Rawat et al.
Journal of controlled release : official journal of the Controlled Release Society, 128(3), 224-232 (2008-05-13)
This study tests the feasibility of large porous particles as long-acting carriers for pulmonary delivery of low molecular weight heparin (LMWH). Microspheres were prepared with a biodegradable polymer, poly(lactic-co-glycolic acid) (PLGA), by a double-emulsion-solvent-evaporation technique. The drug entrapment efficiencies of
Surfactant-stabilized microbubbles as ultrasound contrast agents: stability study of [TM="Span"] 60 and Tween 80 mixtures using a Langmuir trough
Singhal, S., et al.
Langmuir, 9, 2426-2426 (1993)
Sepideh Khoee et al.
European journal of medicinal chemistry, 44(6), 2392-2399 (2008-11-18)
Preparation, characterization and drug release behavior of loaded polybutyl adipate (PBA) nanocapsules with penicillin-G are described here. The nanocapsules were produced using a double emulsion solvent evaporation technique, using dichloromethane as an organic solvent and Tween and Span as surfactants.
Ajay B Solanki et al.
AAPS PharmSciTech, 8(4), E86-E86 (2008-01-10)
The aim of this study was to investigate the combined influence of 3 independent variables in the preparation of piroxicam proniosomes by the slurry method. A 3-factor, 3-level Box-Behnken design was used to derive a second-order polynomial equation and construct
Varaporn Buraphacheep Junyaprasert et al.
International journal of pharmaceutics, 423(2), 303-311 (2011-12-14)
Ellagic acid (EA) is a potent antioxidant phytochemical substance which has limitation to use due to its poor biopharmaceutical properties, low solubility and low permeability. The aim of the present study was to develop niosomal formulations obtained from the mixture
Prasun Bandyopadhyay et al.
Colloids and surfaces. B, Biointerfaces, 58(1), 68-71 (2007-03-07)
Niosomal hybrid mixtures are prepared with bilayer stabilizer cholesterol from non-ionic surfactants span 20 (HLB value 8.6), span 60 (HLB 4.7) and span 85 (HLB 1.8) in presence of dicetyl phosphate (DCP) where fatty acids or fatty alcohols (C14, C16
Payam Khazaeli et al.
Drug delivery, 14(7), 447-452 (2007-11-13)
We prepared different neutral and positively charged niosomal formulations containing sorbitan esters for entrapment of caffeine. Drug entrapment reduced following the incorporation of positively charged molecule. Furthermore, the span 60-containing niosomes showed the highest drug encapsulation efficiency due to solid-state
Yvette Meissner et al.
International journal of pharmaceutics, 335(1-2), 147-153 (2006-12-08)
Low molecular weight heparins (LMWH) have shown efficacy in the treatment of inflammatory bowel disease after parenteral administration however risking severe hemorrhagic adverse effects. Therefore, an oral colonic targeted heparin dosage form allowing the release of LMWH directly in the
Juan He et al.
Journal of separation science, 33(21), 3409-3414 (2010-10-12)
Molecularly imprinted microspheres (MIMs) were prepared by suspension polymerization for the binding and recognition of dibutyl phthalate (DBP). DBP was used as the template molecule, methacrylic acid as the functional monomer, ethylene dimethacrylate (EDMA) as the linking agent, PVA as
Shilpa Kakkar et al.
International journal of pharmaceutics, 413(1-2), 202-210 (2011-05-05)
The work describes usefulness of a novel, surfactants based elastic vesicular drug carrier system (spanlastics), for targeting topically applied drug(s) to the posterior segment of the eye. The system constituted span 60 and a edge activator (tween 80). Ketoconazole, a
Ahmed A Aboelwafa et al.
AAPS PharmSciTech, 11(4), 1591-1602 (2010-11-11)
The aim of this work was to investigate the effects of formulation variables on development of carvedilol (CAR) proniosomal gel formulations as potential transdermal delivery systems. Different non-ionic surfactants; polyoxyethylene alkyl ethers, namely Brij 78, Brij 92, and Brij 72;
Ismail A Attia et al.
AAPS PharmSciTech, 8(4), E106-E106 (2008-01-10)
The purpose of this research was to prepare acyclovir niosomes in a trial to improve its poor and variable oral bioavailability. The nonionic surfactant vesicles were prepared by the conventional thin film hydration method. The lipid mixture consisted of cholesterol
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