MilliporeSigma
Search Within

S7401

Applied Filters:
Keyword:'S7401'
Showing 1-30 of 249 results for "S7401" within Papers
Sevim Beyza Oztürk Sarikaya et al.
Bioorganic & medicinal chemistry letters, 21(14), 4259-4262 (2011-06-15)
Carbonic anhydrase inhibitors (CAIs) are a class of pharmaceuticals used as antiglaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, gastric and duodenal ulcers, neurological disorders or osteoporosis. We report here the inhibitory capacities of some phenolic compounds against
Anton Brosig et al.
Molecular vision, 21, 1000-1016 (2015-09-04)
The pathogenesis of age-related macular degeneration (AMD) is associated with systemic and local inflammation. Various studies suggested that viral or bacterial infection may aggravate retinal inflammation in the aged retina. We compared the effects of synthetic viral RNA (poly(I:C)) and
A Guerra et al.
European journal of medicinal chemistry, 45(3), 930-940 (2009-12-22)
A neural model based on a numerical molecular representation using CODES program to predict oral absorption of any structure is described. This model predicts both high and low-absorbed compounds with a global accuracy level of 74%. CODES/ANN methodology shows promising
Tsuyoshi Saitoh et al.
Bioorganic & medicinal chemistry letters, 19(18), 5383-5386 (2009-08-12)
Dehydroxymethylepoxyquinomicin (DHMEQ, 1) is a novel nuclear factor-kappaB (NF-kappaB) inhibitor that inhibits DNA binding of NF-kappaB components including p65. To inspect its biological activity of 1, we synthesized parasitenone (3), possessing the common epoxycyclohexenone moiety of 1. Assessment of the
Yuhong Li et al.
The journal of physical chemistry. B, 117(12), 3337-3344 (2013-02-28)
The adsorption process of salicylic acid (SA) onto chitosan membrane is monitored in real time by the dielectric relaxation spectroscopy (DRS) method. A unique dielectric relaxation, which is related to the macroscale concentration polarization layers (CPLs) in the SA solution
Zhang Shu-Ling et al.
Indian journal of biochemistry & biophysics, 49(6), 405-413 (2013-01-29)
WRKY transcription factor proteins play important roles in diverse stress responses. In this study, we first cloned a novel WRKY from our constructed bacteriophage full-length cDNA library for cotton (Gossypium barbadense). The plants were stressed by exposure to a defoliating
Mireia Núñez et al.
Analytical and bioanalytical chemistry, 407(13), 3841-3849 (2015-03-18)
A method for the quantitative determination of seven pharmaceuticals in bivalves was developed by QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) extraction, followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) with electrospray ionization. Both the European Standard Method EN 15662
Zheng Qing Fu et al.
Annual review of plant biology, 64, 839-863 (2013-02-05)
Systemic acquired resistance (SAR) is an induced immune mechanism in plants. Unlike vertebrate adaptive immunity, SAR is broad spectrum, with no specificity to the initial infection. An avirulent pathogen causing local programmed cell death can induce SAR through generation of
Kohki Yoshimoto
Autophagy, 6(1), 192-193 (2009-12-22)
It has long been recognized that autophagy in plants is important for nutrient recycling and plays a critical role in the ability of plants to adapt to environmental extremes such as nutrient deprivation. Recent reverse genetic studies, however, hint at
Abdul Latif Khan et al.
BMC microbiology, 13, 51-51 (2013-03-05)
Water-deficiency adversely affects crop growth by generating reactive oxygen species (ROS) at cellular level. To mitigate such stressful events, it was aimed to investigate the co-synergism of exogenous salicylic acid (SA) and symbiosis of endophytic fungus with Capsicum annuum L.
Yashoda Chandorkar et al.
Biomacromolecules, 16(2), 636-649 (2015-01-07)
There has been a continuous surge toward developing new biopolymers that exhibit better in vivo biocompatibility properties in terms of demonstrating a reduced foreign body response (FBR). One approach to mitigate the undesired FBR is to develop an implant capable
M M Vila et al.
Journal of AOAC International, 84(5), 1363-1369 (2001-10-17)
A flow injection (FI) enzymatic system, based on the use of immobilized salicylate hydroxylase in glass beads, was developed for the determination of salicylate. Salicylate hydroxylase and nicotinamide adenine dinucleotide (NADH) are used to convert salicylate to catechol. The reaction
M L Castillo-García et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 985, 85-90 (2015-02-11)
A new method based on ultra high performance liquid chromatography (UPLC) with photometric and fluorometric detection for the determination of acetylsalicylic acid and its main metabolites, namely gentisic, salicylic and salicyluric acids, in bovine urine samples is reported. Photometric detection
Janet Laird et al.
The Journal of general virology, 94(Pt 12), 2777-2789 (2013-10-04)
Cauliflower mosaic virus (CaMV) encodes a 520 aa polypeptide, P6, which participates in several essential activities in the virus life cycle including suppressing RNA silencing and salicylic acid-responsive defence signalling. We infected Arabidopsis with CaMV mutants containing short in-frame deletions
Burcu Seckin Dinler et al.
Acta biologica Hungarica, 65(4), 469-480 (2014-12-06)
In the present study, the effect of ascorbic acid (5 mM) on some physiological parameters and three hormones (auxin, abscisic acid, salicylic acid) was determined under heat stress (40 °C) in maize tolerant cv. (MAY 69) and sensitive cv. SHEMAL
Kimiko Fukuoka et al.
Biodegradation, 26(5), 359-373 (2015-07-02)
3-Methylindole, also referred to as skatole, is a pollutant of environmental concern due to its persistence, mobility and potential health impacts. Petroleum refining, intensive livestock production and application of biosolids to agricultural lands result in releases of 3-methylindole to the
David Buttar et al.
Bioorganic & medicinal chemistry, 18(21), 7486-7496 (2010-09-28)
The displacement of probes that bind selectively to subdomains IIA or IIIA on human serum albumin (HSA) by competing compounds has been followed using fluorescence spectroscopy, and has therefore been used to assign a primary binding site for these compounds
J Musembi Mutuku et al.
Plant physiology, 168(3), 1152-1163 (2015-05-31)
The root hemiparasite witchweed (Striga spp.) is a devastating agricultural pest that causes losses of up to $1 billion US annually in sub-Saharan Africa. Development of resistant crops is one of the cost-effective ways to address this problem. However, the
Gregory Kaler et al.
The Journal of biological chemistry, 282(33), 23841-23853 (2007-06-08)
Organic anion transporters (OATs, SLC22) interact with a remarkably diverse array of endogenous and exogenous organic anions. However, little is known about the structural features that determine their substrate selectivity. We examined the substrate binding preferences and transport function of
Jason T Bau et al.
Molecular pharmacology, 85(2), 198-207 (2013-11-14)
Topoisomerase II (topo II) is a ubiquitous enzyme that is essential for cell survival through its role in regulating DNA topology and chromatid separation. Topo II can be poisoned by common chemotherapeutics (such as doxorubicin and etoposide), leading to the
Seung Ho Chung et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(39), 15728-15733 (2013-09-11)
Induced plant defenses in response to herbivore attack are modulated by cross-talk between jasmonic acid (JA)- and salicylic acid (SA)-signaling pathways. Oral secretions from some insect herbivores contain effectors that overcome these antiherbivore defenses. Herbivores possess diverse microbes in their
Chuanfu An et al.
Journal of integrative plant biology, 53(6), 412-428 (2011-05-04)
The small phenolic compound salicylic acid (SA) plays an important regulatory role in multiple physiological processes including plant immune response. Significant progress has been made during the past two decades in understanding the SA-mediated defense signaling network. Characterization of a
Fansuo Zeng et al.
PloS one, 9(12), e116157-e116157 (2015-01-01)
Evidence supporting nitric oxide (NO) as a mediator of plant biochemistry continues to grow, but its functions at the molecular level remains poorly understood and, in some cases, controversial. To study the role of NO at the transcriptional level in
N I Vasiukova et al.
Prikladnaia biokhimiia i mikrobiologiia, 43(4), 405-411 (2007-10-13)
Current understanding of the involvement of salicylic acid (SA) in the formation of plant resistance has been reviewed. SA acts as a signal molecule in the SA-dependent pathway. The so-called salicylate burst observed in tissues of plants after stress increases
Rona Reibis et al.
Current medical research and opinion, 31(2), 211-219 (2014-10-18)
We aimed to describe the contemporary management of patients with systolic chronic heart failure (CHF) during a cardiac rehabilitation (CR) stay and present outcomes with focus on lipids, blood pressure, exercise capacity, and clinical events. Comparison of 3199 patients with
Jo Ann E Asselin et al.
Plant physiology, 167(3), 1117-1135 (2015-01-31)
AvrE family type III effector proteins share the ability to suppress host defenses, induce disease-associated cell death, and promote bacterial growth. However, despite widespread contributions to numerous bacterial diseases in agriculturally important plants, the mode of action of these effectors
V A Halim et al.
Plant biology (Stuttgart, Germany), 8(3), 307-313 (2006-06-30)
Phytohormones are not only instrumental in regulating developmental processes in plants but also play important roles for the plant's responses to biotic and abiotic stresses. In particular, abscisic acid, ethylene, jasmonic acid, and salicylic acid have been shown to possess
Katrin Scheit et al.
Carcinogenesis, 36(3), 400-411 (2015-02-06)
Salicylic acid and anthocyanidins are known as plant-derived antioxidants, but also can provoke paradoxically seeming prooxidant effects in vitro. These prooxidant effects are connected to the potential of salicylic acid and anthocyanidins to induce apoptosis selectively in tumor cells in
Julia Martín et al.
The Science of the total environment, 503-504, 97-104 (2014-06-10)
Sewage sludge disposal onto lands has been stabilized previously but still many pollutants are not efficiently removed. Special interest has been focused on pharmaceutical compounds due to their potential ecotoxicological effects. Nowadays, there is scarce information about their occurrence in
Denis Fourches et al.
Chemical research in toxicology, 23(1), 171-183 (2009-12-18)
Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this
Page 1 of 9