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Showing 1-30 of 1432 results for "S8045" within Papers
Jie Xiao et al.
Journal of agricultural and food chemistry, 63(47), 10263-10270 (2015-11-06)
Kafirin nanoparticle-stabilized Pickering emulsions (KPEs) were used to encapsulate curcumin. The stability of KPEs under processing conditions and their protective effects against photo-oxidation of curcumin and lipid oxidation of oil in emulsions, as well as the digestion profiles in gastrointestinal
N G R Dayan Elshan et al.
Organic & biomolecular chemistry, 13(6), 1778-1791 (2014-12-17)
Melanocortin receptors can be used as biomarkers to detect and possibly treat melanoma. To these ends, molecules bearing one, two, or three copies of the weakly binding ligand MSH(4) were attached to scaffolds based on phloroglucinol, tripropargylamine, and 1,4,7-triazacyclononane by
S Syama et al.
Toxicology mechanisms and methods, 24(9), 644-653 (2014-08-21)
Engineered nanoparticles are developed for various applications in industrial, electrical, agricultural, pharmaceutical and medical fields due to their unique properties. Nanoparticles such as TiO(2) and ZnO are widely used in cosmetics for UV protection. The toxicological investigations of ZnO NPs
Julia Misiewicz et al.
Biochimica et biophysica acta, 1848(3), 833-841 (2014-12-17)
To understand the molecular mechanisms of amphiphilic membrane-active peptides, one needs to study their interactions with lipid bilayers under ambient conditions. However, it is difficult to control the pH of the sample in biophysical experiments that make use of mechanically
Sonia Lefnaoui et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 23(6), 698-711 (2015-12-25)
A pregelatinized starch (PGS) was derivatized with sodium chloroacetate (SCA) in alcoholic medium under alkaline condition to produce carboxymethyl pregelatinized starch (CMPGS) with various degrees of substitution (DS). Influence of the molar ratio of SCA to the glucopyranose units (SCA/GU)
Shogo Sasaki et al.
Journal of bioscience and bioengineering, 119(2), 200-205 (2014-07-26)
We demonstrated the synthesis of molecularly imprinted polymers (MIPs) with binding affinity toward a target protein, ribonuclease A (RNase) by atom transfer radical polymerization (ATRP) of acrylic acid, acrylamide, and N,N'-methylenebisacrylamide in the presence of RNase. The binding activity of
Daman Kumari et al.
Human mutation, 35(12), 1485-1494 (2014-09-17)
Fragile X syndrome (FXS) is the most frequent cause of inherited intellectual disability and autism. It is caused by the absence of the fragile X mental retardation 1 (FMR1) gene product, fragile X mental retardation protein (FMRP), an RNA-binding protein
Andrew N Bankston et al.
Bio-protocol, 7(13) (2017-09-05)
Cdk5 activity is regulated by the amounts of two activator proteins, p35 and p39 (Tsai et al., 1994; Zheng et al., 1998; Humbert et al., 2000). The p35-Cdk5 and p39-Cdk5 complexes have differing sensitivity to salt and detergent concentrations (Hisanaga
Sung Ha Ryu et al.
Journal of toxicology and environmental health. Part A, 78(20), 1299-1309 (2015-10-31)
Red ginseng (RG) is one of the top selling herbal medicines in Korea, but is not recommended in hypertensive patients. In this study, the pharmacokinetic (PK) interaction between RG and losartan, an antihypertensive drug, was examined. RG was orally administered
Mary Beth Hall et al.
Journal of microbiological methods, 118, 147-151 (2015-09-22)
Microbial glycogen measurement is used to account for fates of carbohydrate substrates. It is commonly applied to washed cells or pure cultures which can be accurately subsampled, allowing the use of smaller sample sizes. However, the nonhomogeneous fermentation pellets produced
Wenjun Wang et al.
Journal of food science, 80(10), C2117-C2126 (2015-09-17)
Mature-green cherry tomato fruits (Lycopersicon esculentum cv. Jinyu) were exposed to different power densities of ultrasound (66.64, 106.19, and 145.74 W/L) at 25 °C to study ultrasound non-thermal effects on the storage properties. Among the three levels of ultrasound irradiation
Xian-Bing Xu et al.
Journal of chromatography. A, 1366, 65-72 (2014-09-24)
A novel interface that enables high-performance anion-exchange chromatography (HPAEC) to be coupled with electrospray ionization (ESI) mass spectrometry (MS) is reported. A sheath liquid consisting of 50mM NH4Ac in isopropanol with 0.05% acetic acid, infused at a flow rate of
Linlin Liu et al.
Talanta, 114, 243-247 (2013-08-21)
In the present work, a flow injection (FI) "turn off-on" chemiluminescent method was developed for the determination of glutathione (GSH). Strong chemiluminescence (CL) signals were observed from the hydrogen peroxide and CdTe quantum dots (QDs) system under basic condition, addition
Shu-Ling Lin et al.
Talanta, 147, 199-206 (2015-11-26)
In this study, recently developed 1,6-hexanediol ethoxylate diacrylate (HEDA)-based polymeric monoliths were utilized as sorbents for efficient extraction of phenylurea herbicides (PUHs) from water samples. The HEDA-based monolithic sorbents were prepared in a fused silica capillary (0.7mm i.d., 4.5-cm long)
Jianqing Chen et al.
Pharmaceutical research, 31(10), 2810-2821 (2014-05-23)
To assess the application of succinimidyl iodobenzoate (SIB) iodination method in labeling biotherapeutics to study their pharmacokinetics (PK) and biodistribution. An IgG molecule (protein-01) and a 40 KDa protein (protein-02) were evaluated. Pharmacokinetics (PK) and biodistribution of the radiolabeled IgG ((125)I-protein-01)
Amirah Al-Attas et al.
Biomedical chromatography : BMC, 29(12), 1811-1818 (2015-06-11)
A green, novel, rapid, accurate and reliable capillary zone electrophoresis method was developed and validated for the simultaneous determination of piperacillin, tazobactam and cefepime in pharmaceutical preparations. Separation was carried out using fused silica capillary (50 µm i.d. × 48.6 cm and 40.2 cm detection
Orlagh M Feeney et al.
Journal of controlled release : official journal of the Controlled Release Society, 192, 219-227 (2014-07-25)
For over 20years, stealth drug delivery has been synonymous with nanoparticulate formulations and intravenous dosing. The putative determinants of stealth in these applications are the molecular weight and packing density of a hydrophilic polymer (commonly poly(ethylene glycol) (PEG)) that forms
Elizabeth A Baldwin et al.
PeerJ, 3, e1398-e1398 (2015-12-09)
Background. Preterm Premature Rupture of Membranes (PPROM) is a major leading cause of preterm births. While the cause for PPROM remains unidentified, it is anticipated to be due to subclinical infection, since a large proportion of PPROM patients display signs
Delia Spanò et al.
Protein expression and purification, 116, 152-158 (2015-09-01)
This paper deals with the purification of a class III endochitinase from Euphorbia characias latex. Described purification method includes an effective novel separation step using magnetic chitin particles. Application of magnetic affinity adsorbent noticeably simplifies and shortens the purification procedure.
Sarah Unser et al.
The Analyst, 140(2), 590-599 (2014-11-27)
Development of improved glucose detection has vast significance in both clinical and point of care settings. Herein, we present a novel, label-free, enzyme-free, colorimetric method of glucose detection that relies on the reduction of a gold salt precursor facilitated by
Ali Es-Haghi et al.
Talanta, 128, 231-236 (2014-07-26)
Sol-gel based solid-phase microextraction fibers supported by a stainless steel wire were fabricated and employed for GC-MS determination of oxadiargyl in real samples. The fibers were based on four compounds with different polarity: polar and non-polar (end-capped) poly(dimethylsiloxane) (PDMS), polyethylene
Lucy G Chastain et al.
Behavioural brain research, 280, 160-171 (2014-12-03)
Schizophrenia is thought to be caused, at least in part, by dysfunction in striatal dopamine neurotransmission. Both clinical studies and animal research have implicated the dopamine neuromodulator neurotensin (NT) in the pathophysiology of schizophrenia. Utilizing male mice lacking the NT
Davy Baudelet et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 986-987, 35-43 (2015-02-24)
The P2X receptors are seven-transmembrane domain G protein-coupled receptors and the 7 subtypes of P2X receptors identified in humans, and named P2X1 to P2X7, are channel receptors whose endogenous ligand is ATP. New antagonists of the P2X7 receptor were developed
Hai-Bo He et al.
Journal of chromatography. A, 1361, 23-33 (2014-08-31)
This paper reports a nanomagnetic polyhedral oligomeric silsesquioxanes (POSS)-directing strategy toward construction of molecularly imprinted hybrid materials for antibiotic residues determination in milk samples. The imprinted polymeric layer was facilely obtained through the copolymerization of active vinyl groups present on
Venkata V V R Marada et al.
Pharmacological research, 91, 78-87 (2014-12-08)
The ability of an antineoplastic drug to exert its cytostatic effect depends largely on the balance between its uptake into and extrusion from the cancer cells. ATP driven efflux transporter proteins drive the export of antineoplastic drugs and play a
Quan Chi et al.
Luminescence : the journal of biological and chemical luminescence, 30(7), 990-995 (2015-02-03)
The chemiluminescence (CL) of lucigenin (Luc(2+)) can be enhanced by different alcohols in alkaline solution. The effect of different fatty alcohols on the CL of lucigenin was related to the carbon chain length and the number of hydroxyl groups. Glycerol
Rokhsana Yasmin et al.
Journal of pharmaceutical sciences, 103(9), 2950-2959 (2014-03-04)
Lyophilization was investigated to produce a powdery silica-lipid hybrid (SLH) carrier for oral delivery of poorly water-soluble drugs. The silica to lipid ratio, incorporation of cryoprotectant, and lipid loading level were investigated as performance indicators for lyophilized SLH carriers. Celecoxib
M Argun et al.
Eye (London, England), 28(6), 752-760 (2014-03-08)
Under conditions of oxidative stress, cell apoptosis is triggered through the mitochondrial intrinsic pathway. Increased levels of reactive oxygen species (ROS) are linked to excess cell loss and mediate the initiation of apoptosis in a diverse range of cell types.
Marcos Tascon et al.
Analytical and bioanalytical chemistry, 407(13), 3637-3645 (2015-03-10)
The use of algae as a foodstuff is rapidly expanding worldwide from the East Asian countries, where they are also used for medical care. Harmala alkaloids (HAlk) are a family of bioactive compounds found in the extracts of some plants
Dietmar Reusch et al.
mAbs, 7(1), 167-179 (2014-12-20)
Immunoglobulin G (IgG) crystallizable fragment (Fc) glycosylation is crucial for antibody effector functions, such as antibody-dependent cell-mediated cytotoxicity, and for their pharmacokinetic and pharmacodynamics behavior. To monitor the Fc-glycosylation in bioprocess development, as well as product characterization and release analytics
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