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Showing 1-18 of 18 results for "SAB4600234" within Papers
Aihua Hou et al.
Eye and vision (London, England), 4, 17-17 (2017-07-15)
Gram-positive bacteria stimulate Toll-like receptor (TLR) 2 and then activate the pro-inflammatory nuclear factor-kappa B (NF-κB) pathway. As the human ocular surface is heavily colonised by gram-positive cocci bacteria, a balance of activation/repression of NF-κB target genes is essential to
Plastic embedding immunolabeled large-volume samples for three-dimensional high-resolution imaging.
Gang Y, et al.
Biomedical Optics Express, 8(8), 3583-3596 (2017)
Simona Manta et al.
Journal of controlled release : official journal of the Controlled Release Society, 262, 170-181 (2017-07-16)
Despite the increasing number of clinical trials in gene therapy, no ideal methods still allow non-viral gene transfer in deep tissues such as the liver. We were interested in ultrasound (US)-mediated gene delivery to provide long term liver expression. For
Antibody structure, instability, and formulation.
Wang W
Journal of Pharmaceutical Sciences, 96(1), 1-26 (2007)
Xuehui Yu et al.
American journal of cancer research, 12(10), 4825-4839 (2022-11-17)
Glioblastoma (GBM) is the most frequently observed and aggressive type of high-grade malignant glioma. Temozolomide (TMZ) is the primary agent for GBM treatment. However, TMZ resistance remains a major challenge. In this study, we report that MDK is overexpressed in
Toll-like receptor 2-mediated NF-kappa B pathway activation in ocular surface epithelial cells.
Hou A, et al.
Eye and Vision (London, England), 4(1), 17-17 (2017)
Jordi Camps et al.
International journal of molecular sciences, 20(5) (2019-03-08)
Progressive muscle degeneration followed by dilated cardiomyopathy is a hallmark of muscular dystrophy. Stem cell therapy is suggested to replace diseased myofibers by healthy myofibers, although so far, we are faced by low efficiencies of migration and engraftment of stem
Yuan Jiang et al.
Communications biology, 5(1), 716-716 (2022-07-20)
Myocardial ischemia/reperfusion (MI/R) injury is a pathological process that seriously affects the health of patients with coronary artery disease. Long non-coding RNAs (lncRNAs) represents a new class of regulators of diverse biological processes and disease conditions, the study aims to
Metformin ameliorates sepsis-induced brain injury by inhibiting apoptosis, oxidative stress and neuroinflammation via the PI3K/Akt signaling pathway.
Tang G, et al.
Oncotarget, 8(58), 97977-97977 (2017)
Aubree Jones et al.
Anatomical record (Hoboken, N.J. : 2007), 302(10), 1837-1845 (2019-04-14)
Our understanding of vibrissal function in pinnipeds is poor due to the lack of comparative morphological, neurobiological, and psychophysical performance data. In contrast, the function of terrestrial mammalian vibrissae is better studied. Pinnipeds have the largest vibrissae of all mammals
Jordi Camps et al.
Cell reports, 31(5), 107597-107597 (2020-05-07)
Fibrosis and fat replacement in skeletal muscle are major complications that lead to a loss of mobility in chronic muscle disorders, such as muscular dystrophy. However, the in vivo properties of adipogenic stem and precursor cells remain unclear, mainly due to
Zhilan Li et al.
American journal of cancer research, 10(7), 2083-2099 (2020-08-11)
Anoikis resistance is an important mechanism that mediates tumor metastasis. Studies have found that Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) promotes the occurrence, development, and metastasis of nasopharyngeal carcinoma (NPC). However, the related mechanism, especially whether LMP1 is
Specific IgG for cat allergens in patients with allergic conjunctivitis.
Miyama A, et al.
International Ophthalmology, 35(4), 575-586 (2015)
Cielo Mae D Marquez et al.
Asian Pacific journal of cancer prevention : APJCP, 21(8), 2453-2461 (2020-08-29)
The chemotherapy drug doxorubicin (DOX) is effective in treating many types of cancers. However, due to its pro-inflammatory and cardiotoxic side effects, other remedies have also been explored as alternative treatments. The plant Alangium longiflorum was reported to contain cytotoxic
Emily H Bowler et al.
Epigenetics, 15(1-2), 107-121 (2019-08-27)
DNA methyltransferase I plays the central role in maintenance of CpG DNA methylation patterns across the genome and alteration of CpG methylation patterns is a frequent and significant occurrence across many cancers. Cancer cells carrying hypomorphic alleles of Dnmt1 have
Guangming Tang et al.
Oncotarget, 8(58), 97977-97989 (2017-12-13)
Sepsis-induced brain injuries increase mortality, morbidity, cognitive impairment and lack of effective therapeutic treatment. Previous studies have suggested that metformin provides neuroprotective effects against ischemia, brain trauma and other brain damage, but whether metformin protects a septic brain remains unknown.
Zhe-Long Jin et al.
Journal of cell science, 131(23) (2018-11-09)
Dynamic reorganization of the actin cytoskeleton is fundamental to a number of cellular events, and various actin-regulatory proteins modulate actin polymerization and depolymerization. Adenylyl cyclase-associated proteins (CAPs), highly conserved actin monomer-binding proteins, have been known to promote actin disassembly by
Johannes Walter et al.
International journal of molecular sciences, 24(16) (2023-08-26)
Activation of the interleukin-4 (IL-4) pathway ameliorates secondary injury mechanisms after experimental traumatic brain injury (TBI); therefore, we assessed the effect of a therapeutic IL-4 administration on secondary brain damage after experimental TBI. We subjected 100 C57/Bl6 wildtype mice to
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