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Showing 1-13 of 13 results for "SAB4700215" within Papers
The protein CD63 is in platelet dense granules, is deficient in a patient with Hermansky-Pudlak syndrome, and appears identical to granulophysin.
Nishibori M
The Journal of Clinical Investigation, 91, 1775-1782 (1993)
Expression of the tetraspanins CD9, CD37, CD63, and CD151 in Merkel cell carcinoma: strong evidence for a posttranscriptional fine-tuning of CD9 gene expression.
Woegerbauer M
Modern Pathology, 23, 751-762 (2010)
A novel link between integrins, transmembrane-4 superfamily proteins (CD63 and CD81), and phosphatidylinositol 4-kinase.
Berditchevski F
The Journal of Biological Chemistry, 272, 2595-2598 (1997)
Improved metabolic control decreases platelet activation markers in patients with type-2 diabetes.
Eibl N
European Journal of Clinical Investigation, 34, 205-209 (2004)
Satoshi Murakami et al.
Scientific reports, 9(1), 671-671 (2019-01-27)
IgG is an indispensable biological experimental tool as well as a widely-used therapeutic protein. However, cell culture-based expression of monoclonal IgG is costly and time-consuming, making this process difficult to use for high-throughput screening in early-stage evaluation of biologics. With
Victor H Villar et al.
Nature communications, 8, 14124-14124 (2017-01-24)
A master coordinator of cell growth, mTORC1 is activated by different metabolic inputs, particularly the metabolism of glutamine (glutaminolysis), to control a vast range of cellular processes, including autophagy. As a well-recognized tumour promoter, inhibitors of mTORC1 such as rapamycin
Jayanthi Lea et al.
Oncotarget, 8(9), 14395-14407 (2017-01-26)
There are no suitable screening modalities for ovarian carcinomas (OC) and repeated imaging and CA-125 levels are often needed to triage equivocal ovarian masses. Definitive diagnosis of malignancy, however, can only be established by histologic confirmation. Thus, the ability to
Gene expression signature associated with BRAF mutations in human primary cutaneous melanomas
Kannengiesser C
Molecular Oncology, 1, 425-430 (2008)
Raffaele Nicastro et al.
eLife, 11 (2022-07-30)
The essential biometal manganese (Mn) serves as a cofactor for several enzymes that are crucial for the prevention of human diseases. Whether intracellular Mn levels may be sensed and modulate intracellular signaling events has so far remained largely unexplored. The
Tra-Ly Nguyen et al.
Cancer research, 78(18), 5384-5397 (2018-07-29)
The mTOR is a central regulator of cell growth and is highly activated in cancer cells to allow rapid tumor growth. The use of mTOR inhibitors as anticancer therapy has been approved for some types of tumors, albeit with modest
Tuomas Kaprio et al.
PloS one, 14(2), e0211564-e0211564 (2019-02-16)
Ornithine decarboxylase (ODC) is the rate-limiting enzyme of polyamine synthesis. The two ODC antizyme inhibitors (AZIN1) and (AZIN2) are regulators of the catalytic activity of ODC. While AZIN1 is a regulator of cell proliferation, AZIN2 is involved in intracellular vesicle
Detection of phosphatidylserine-positive exosomes as a diagnostic marker for ovarian malignancies: a proof of concept study
Lea J,
Oncotarget, 8, 14395-14407 (2017)
Kahia Messaoudi et al.
Nature communications, 8(1), 1786-1786 (2017-11-28)
Thrombocytopenia is a major side effect of a new class of anticancer agents that target histone deacetylase (HDAC). Their mechanism is poorly understood. Here, we show that HDAC6 inhibition and genetic knockdown lead to a strong decrease in human proplatelet
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