SBR00022

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Showing 1-8 of 8 results for "SBR00022" within Papers

Blasticidin S Deaminase: A New Efficient Selectable Marker for Chlamydomonas reinhardtii.

Félix de Carpentier et al.

Frontiers in plant science, 11, 242-242 (2020-03-27)

Chlamydomonas reinhardtii is a model unicellular organism for basic or biotechnological research, such as the production of high-value molecules or biofuels thanks to its photosynthetic ability. To enable rapid construction and optimization of multiple designs and strains, our team and

Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome.

Egor Svidritskiy et al.

Proceedings of the National Academy of Sciences of the United States of America, 110(30), 12283-12288 (2013-07-05)

The antibiotic blasticidin S (BlaS) is a potent inhibitor of protein synthesis in bacteria and eukaryotes. We have determined a 3.4-Å crystal structure of BlaS bound to a 70S⋅tRNA ribosome complex and performed biochemical and single-molecule FRET experiments to determine

Induction of TLR-2 and TLR-5 expression by Helicobacter pylori switches cagPAI-dependent signalling leading to the secretion of IL-8 and TNF-α.

Suneesh Kumar Pachathundikandi et al.

PloS one, 6(5), e19614-e19614 (2011-05-17)

Helicobacter pylori is the causative agent for developing gastritis, gastric ulcer, and even gastric cancer. Virulent strains carry the cag pathogenicity island (cagPAI) encoding a type-IV secretion system (T4SS) for injecting the CagA protein. However, mechanisms of sensing this pathogen

Hemoglobin transforms anti-inflammatory Salmonella typhi virulence polysaccharide into a TLR-2 agonist.

Rohini Garg et al.

Journal of immunology (Baltimore, Md. : 1950), 184(11), 5980-5987 (2010-05-05)

Vi capsular polysaccharide is a major virulence determinant of the human typhoid- causing pathogen Salmonella typhi; it is absent in nontyphoidal Salmonella serovars. We show in this study that through its specific interaction with the membrane recognition complex containing the

Dopamine targets cycling B cells independent of receptors/transporter for oxidative attack: Implications for non-Hodgkin's lymphoma.

Elizabeth J Meredith et al.

Proceedings of the National Academy of Sciences of the United States of America, 103(36), 13485-13490 (2006-08-30)

Human B lymphocytes and derived lines from a spectrum of B cell malignancy were studied for expression of dopaminergic pathway components and for their cytostatic response to the catecholamine and related, potentially therapeutic compounds. Proliferating normal lymphocytes and dividing malignant

Mechanism of Inhibition of Translation Termination by Blasticidin S.

Egor Svidritskiy et al.

Journal of molecular biology, 430(5), 591-593 (2018-01-26)

Understanding the mechanisms of inhibitors of translation termination may inform development of new antibacterials and therapeutics for premature termination diseases. We report the crystal structure of the potent termination inhibitor blasticidin S bound to the ribosomal 70S•release factor 1 (RF1)

Synergic activation of toll-like receptor (TLR) 2/6 and 9 in response to Ureaplasma parvum & urealyticum in human amniotic epithelial cells.

Martha Triantafilou et al.

PloS one, 8(4), e61199-e61199 (2013-04-18)

Ureaplasma species are the most frequently isolated microorganisms inside the amniotic cavity and have been associated with spontaneous abortion, chorioamnionitis, premature rupture of the membranes (PROM), preterm labour (PL) pneumonia in neonates and bronchopulmonary dysplasia in neonates. The mechanisms by

A rice fungicide blasticidin S efficiently binds Cu(II) ions and prevents DNA from metal-induced damage.

Kamila Stokowa-Sołtys et al.

Journal of inorganic biochemistry, 127, 73-78 (2013-07-25)

Blasticidin S is a representative of the aminoacylnucleoside class of antibiotics and it possesses fungicidal properties against the virulent fungus which causes a serious rice blast disease in Asia. It is widely used to control rice blast by foliar application

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