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Showing 1-7 of 7 results for "SCC134" within Papers
Md Rezaul Islam et al.
EMBO molecular medicine, 13(11), e13659-e13659 (2021-10-12)
While some individuals age without pathological memory impairments, others develop age-associated cognitive diseases. Since changes in cognitive function develop slowly over time in these patients, they are often diagnosed at an advanced stage of molecular pathology, a time point when
Akiko Nakano-Doi et al.
International journal of molecular sciences, 24(2) (2023-01-22)
Microglial cells (MGs), originally derived from progenitor cells in a yolk sac during early development, are glial cells located in a physiological and pathological brain. Since the brain contains various cell types, MGs could frequently interact with different cells, such
Yoshinobu Hirano et al.
Cells, 12(16) (2023-08-26)
We previously demonstrated that neural stem/progenitor cells (NSPCs) were induced within and around the ischemic areas in a mouse model of ischemic stroke. These injury/ischemia-induced NSPCs (iNSPCs) differentiated to electrophysiologically functional neurons in vitro, indicating the presence of a self-repair
Zhong-Qing Sun et al.
Neural regeneration research, 17(1), 203-209 (2021-06-09)
Lycium barbarum (LB) is a traditional Chinese medicine that has been demonstrated to exhibit a wide variety of biological functions, such as antioxidation, neuroprotection, and immune modulation. One of the main mechanisms of Alzheimer's disease is that microglia activated by
Annika Behrendt et al.
Neurobiology of disease, 130, 104518-104518 (2019-06-24)
Tau cleavage by different proteolytic enzymes generates short, aggregation-prone fragments that have been implicated in the pathogenesis of Alzheimer's disease (AD). Asparagine endopeptidase (AEP) activity in particular has been associated with tau dysfunction and aggregation, and the activity of the
Bing-Wen Lu et al.
Advances in ophthalmology practice and research, 3(2), 47-54 (2023-10-17)
Artesunate (ART), a member of the artemisinin family, possesses multi-properties, including anti-inflammation, anti-oxidation, and anti-tumor. ART was recently reported to show anti-neovascularization effect on the cornea, iris, and retina. Compared to the expensive anti-VEGF treatment, this versatile, economical treatment option
Israel C Nnah et al.
Journal of neurochemistry, 154(2), 177-189 (2019-11-07)
Alzheimer's disease (AD) is characterized by accumulation of amyloid-beta (Aβ) senile plaques in patients' brain tissues. Elevated levels of interleukin-1beta (IL-1β) have been identified in cerebrospinal fluid of living AD patients and in animal models of AD. Increased expression of IL-1β
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