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T1199
Keyword:'T1199'
Showing 1-28 of 28 results for "T1199" within Papers
Drug metabolism and disposition: the biological fate of chemicals, 36(8), 1470-1475 (2008-05-21)
The local anesthetics lidocaine (lido) and prilocaine (prilo) are metabolized to their constituent aromatic amines 2,6-dimethylaniline (DMA, 2,6-xylidine) and 2-methylaniline (MA, o-toluidine), respectively, which are both tumorigenic in rats. The capacity of lido and prilo to form DNA adducts was
Rapid specific method for determination of aldosaccharides in body fluids.
Nature, 183(4654), 108-109 (1959-01-10)
An o-toluidine method for body-fluid glucose determination.
Clinical chemistry, 54(11), 1919-1920 (2008-10-30)
Occupational and environmental medicine, 67(5), 348-350 (2009-11-04)
In 1991, the US National Institute for Occupational Safety and Health (NIOSH) reported an increased bladder cancer risk in a cohort of 1749 workers potentially exposed to o-toluidine and aniline at a chemical manufacturing plant. As additional information showed that
Chemosphere, 70(6), 949-957 (2007-09-26)
In this study, major toxicants in pigment wastewaters (i.e. raw wastewater and effluent) were determined by toxicity identification evaluations (TIEs), and changes in their toxicities due to combined gamma-ray (gamma-ray) and ozone treatments were evaluated. From TIE results using Daphnia
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 20(7), 1524-1536 (2011-05-27)
This multicenter, observational study was conducted in three European countries (Germany, Switzerland, and the United Kingdom) to determine the exposure of adult cigarette smokers and nonsmokers to selected cigarette smoke constituents: 1,3-butadiene, 2-naphthylamine, 4-aminobiphenyl, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), acrolein, benzene, carbon monoxide
Talanta, 81(1-2), 664-672 (2010-03-02)
The electrochemical synthesis and characterization of a copolymer, poly(o-toluidine-co-o-aminophenol), were conducted using in situ piezoelectric FTIR spectroelectrochemistry. The monomer feed ratio strongly affects the copolymerization rate and the properties of the copolymer during the electrosynthesis in 0.5M H(2)SO(4) aqueous solution.
Journal of nanoscience and nanotechnology, 7(9), 3117-3125 (2007-11-21)
Poly(ortho-toluidine) (POT)-gold (Au) and palladium (Pd) composite nanospheres were successfully synthesized by the reaction of o-toluidine with the corresponding metal (Au or Pd) colloidal solution through self-assembly process in the presence of dodecylbenzenesulfonic acid (DBSA), which acts as both a
Toxicology in vitro : an international journal published in association with BIBRA, 22(3), 812-818 (2007-12-25)
Aniline (ANI) and the human carcinogen o-toluidine (OT) are released at the workplace during the production and processing of rubber. Recently, we showed in rubber industry workers that a frequent use of skin barrier creams (SBC) increased the internal exposure
Journal of medicinal chemistry, 48(9), 3269-3279 (2005-04-29)
Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm of the partition coefficient of the neutral species in
Lung cancer (Amsterdam, Netherlands), 68(2), 170-176 (2009-12-05)
The use of gas sensor arrays as medical diagnosis instruments has been proposed several years ago. Since then, the idea has been proven for a limited number of diseases. The case of lung cancer is particularly interesting because it is
Environmental science and pollution research international, 19(1), 169-176 (2011-06-28)
The optimal conditions of o-toluidine degradation by fluidized-bed Fenton process were determined using Box-Behnken designs (BBD). The BBD can be used to find the optimal conditions in multivariable systems. The optimal conditions obtained by the design were further applied in
o‑Toluidine and its hydrochloride.
Report on carcinogens : carcinogen profiles, 12, 416-418 (2011-08-25)
Se pu = Chinese journal of chromatography, 28(3), 260-263 (2010-06-17)
Bare nonporous silica particles with diameter around 1 microm were prepared. A 20 cm section of a total length of 45 cm capillary (100 microm i. d.) was packed electrokinetically and the separation performance of basic compounds was investigated in
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 16(2), 120-128 (2010-12-02)
4-Aminobiphenyl (4-ABP) and o-toluidine are known human bladder carcinogens, but only 4-ABP-releasing DNA adducts are known. Determination of 4-ABP and o-toluidine-releasing DNA adducts in epithelial and submucosal bladder tissues of sudden death victims (SDV: n=46), and bladder tumours (n=12) by
Physical chemistry chemical physics : PCCP, 11(21), 4311-4318 (2009-05-22)
The rotationally resolved spectrum of the o-toluidine S(1)<-- S(0) origin was measured using laser induced fluorescence spectroscopy. From the resulting spectrum torsional barriers to internal rotation of the methyl group were derived, which resulted in S(0) state values of V(3)
Journal of hazardous materials, 170(2-3), 928-933 (2009-06-23)
Electrochemical oxidation of O-toluidine (OT) was studied by galvanostatic electrolysis using lead dioxide (PbO2) and boron-doped diamond (BDD) as anodes. The influence of operating parameters, such as current density, initial concentration of OT and temperature was investigated. Measurements of chemical
Archives of toxicology, 85(2), 127-133 (2010-06-16)
The personal use of hair dye products is currently under discussion due to the potentially increased risk of bladder cancer among long-time users described in epidemiological literature. In order to investigate the dermal absorption of aromatic diamines as well as
Occupational and environmental medicine, 72(1), 57-63 (2014-06-11)
Carcinogenic aromatic amines derived from hair dyes have recently received new attention. One of these is ortho (o)-toluidine, which is classified as carcinogenic to humans. To clarify exposure of hairdressers to potentially carcinogenic aromatic amines, including o-toluidine. We measured eight
Journal of occupational and environmental hygiene, 9(8), 478-490 (2012-06-20)
The National Institute for Occupational Safety and Health previously conducted a retrospective cancer incidence and mortality study of workers employed at a rubber chemical manufacturing plant. Compared with New York State incidence, the bladder cancer risk was 6.5 times higher for
International journal of hygiene and environmental health, 212(3), 298-309 (2008-09-16)
The population-based cross-sectional study including 1004 Bavarian volunteers aged 3 up to 84 years (median: 42 years) was aimed to quantify the internal burden of monocyclic arylamines in the general population and to yield reference values. Participants were asked to
Journal of hazardous materials, 196, 395-401 (2011-10-19)
A Box-Behnken design (BBD) statistical experimental design was used to investigate the degradation of o-toluidine by the electro-Fenton process. This method can be used to determine the optimal conditions in multivariable systems. Fe(2+) concentration (0.2-1.0mM), H(2)O(2) concentration (1-5mM), pH (2-4)
Rapid communications in mass spectrometry : RCM, 26(23), 2770-2776 (2012-11-06)
Desorption electrospray ionization (DESI) is the most popular ambient ionization technique for direct analysis of complex samples without sample pretreatment. However, for many applications, especially for trace analysis, it is of interest to improve the sensitivity of DESI-mass spectrometry (MS).
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46(6), 1960-1968 (2008-03-18)
Several aromatic amines (AA) are human carcinogens. AA are widely-used, e.g., in the rubber industry. The uptake of AA at the workplace occurs by inhalation and percutaneous absorption. At present there are no risk assessment studies for percutaneous AA absorption
Applied and environmental microbiology, 73(23), 7759-7762 (2007-10-16)
The rates of metabolism of Sudan I and II and Para Red by human intestinal microflora were high compared to those of Sudan III and IV under anaerobic conditions. Metabolites of the dyes were identified as aniline, 2,4-dimethylaniline, o-toluidine, and
Toxicology and industrial health, 22(9), 367-374 (2007-05-31)
In previous studies from our laboratory, the presence in highly purified liver nuclei of metabolic pathways for processing ethanol (EtOH), N-nitrosodimethylamine (NDMA), carbon tetrachloride and chloroform was reported. All these chemicals are known to be metabolized in liver microsomes, via
Occupational medicine (Oxford, England), 58(7), 496-501 (2008-08-30)
To investigate bladder cancer risks in workers from a factory manufacturing chemicals for the rubber industry. The mortality (1955-2005) and cancer morbidity experience (1971-2005) of a cohort of 2160 male production workers from a chemical factory in north Wales were
Regulatory toxicology and pharmacology : RTP, 64(2), 269-284 (2012-09-04)
o-Toluidine is a monocyclic aromatic amine present in the formulation of some materials that contact drinking water. NSF/ANSI 61 Annex A (2011) and US EPA (2005a) risk assessment guidelines were used to determine an acceptable drinking water level. Occupational exposure
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