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Showing 1-20 of 20 results for "T2815" within Papers
TGF-β superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud
Bush KT, et al.
Developmental Biology, 266, 285-298 (2004)
Christoffer Tengryd et al.
Atherosclerosis, 313, 88-95 (2020-10-09)
A vulnerable plaque is an atherosclerotic plaque that is rupture-prone with a higher risk to cause cardiovascular symptoms such as myocardial infarction or stroke. Mimecan or osteoglycin is a small leucine-rich proteoglycan, important for collagen fibrillogenesis, that has been implicated
B S Betts-Obregon et al.
Eye (London, England), 30(12), 1639-1647 (2016-08-27)
PurposeOne of the earliest hallmarks of diabetic retinopathy is the loss of retinal pericytes. However, the mechanisms that promote pericyte dropout are unknown. In the present study, we propose a novel pathway in which pericyte apoptosis is mediated by macrophages
I Cosgarea et al.
The British journal of dermatology, 186(4), 694-704 (2021-11-14)
For patients with early American Joint Committee on Cancer (AJCC)-stage melanoma the combined loss of the autophagy regulatory protein AMBRA1 and the terminal differentiation marker loricrin in the peritumoral epidermis is associated with a significantly increased risk of metastasis. The
TGF-β1 and TGF-β2 abundance in liver diseases of mice and men
Dropmann A, et al.
Oncotarget, 7(15), 19499?19518-19499?19518 (2016)
Transforming growth factor β (TGF-β) and inflammation in cancer.
Bierie B and Moses HL
Cytokine & Growth Factor Reviews, 21.1, 49-59 (2010)
Preliminary Results of Tissue-Engineered Injection Laryngoplasty
Material in a Rabbit Model
Oldenburg MS, et al.
Laryngoscope, 128, 160-167 (2018)
Tetramethylpyrazine (TMP), an Active Ingredient of Chinese Herb Medicine Chuanxiong, Attenuates the Degeneration of Trabecular Meshwork through SDF-1/CXCR4 Axis
Yu N, et al.
PLoS ONE, 10.8 (2015)
Michael S Oldenburg et al.
The Laryngoscope, 128(1), 160-167 (2017-09-13)
Design and test a novel biomaterial for injection laryngoplasty aimed to increase the duration of effectiveness of micronized acellular dermis. Animal model. Injection laryngoplasty was performed in three groups (n = 5) of New Zealand White rabbits. Acellular dermis was
TGF-β2?induced matrix modification and cell transdifferentiation in the human lens capsular bag
Wormstone IM, et al.
Investigative Ophthalmology & Visual Science, 43.7, 2301-2308 (2002)
Fei Wang et al.
Nature communications, 13(1), 3620-3620 (2022-06-25)
Pigs are valuable large animal models for biomedical and genetic research, but insights into the tissue- and cell-type-specific transcriptome and heterogeneity remain limited. By leveraging single-cell RNA sequencing, we generate a multiple-organ single-cell transcriptomic map containing over 200,000 pig cells
Ajay Ashok et al.
Investigative ophthalmology & visual science, 61(3), 24-24 (2020-03-18)
Elevated levels of transforming-growth-factor (TGF)-β2 in the trabecular meshwork (TM) and aqueous humor are associated with primary open-angle glaucoma (POAG). The underlying mechanism includes alteration of extracellular matrix homeostasis through Smad-dependent and independent signaling. Smad4, an essential co-Smad, upregulates hepcidin
Evaluation of zinc finger E-box binding homeobox 1 and transforming growth factor-β2 expression in bladder cancer tissue in comparison with healthy adjacent tissue
Mahdavinezhad A, et al.
Investigative and Clinical Urology, 58(2), 140?145-140?145 (2017)
Effie E Bastounis et al.
Scientific reports, 9(1), 18209-18209 (2019-12-05)
Endothelial cells respond to changes in subendothelial stiffness by altering their migration and mechanics, but whether those responses are due to transcriptional reprogramming remains largely unknown. We measured traction force generation and also performed gene expression profiling for two endothelial
Na Yu et al.
PloS one, 10(8), e0133055-e0133055 (2015-08-15)
A traditional Chinese medicine, Tetramethylpyrazine (TMP), has been prescribed as a complementary treatment for glaucoma to improve patient prognosis. However, the pharmacological mechanism of action of TMP is poorly understood. In previous studies, we demonstrated that TMP exerts potent inhibitory
Julia Onken et al.
Journal of neuro-oncology, 120(1), 73-83 (2014-07-30)
Versican is a large chondroitin sulphate proteoglycan produced by several tumor cell types, including high-grade gliomas. Increased expression of distinct versican isoforms in the extracellular matrix plays a role in tumor cell growth, adhesion and migration. We have recently shown
A signaling pathway involving TGF-β2 and snail in hair follicle morphogenesis.
Jamora C, et al.
PLoS Biology, 3.1 (2004)
Curcumin suppresses doxorubicin-induced epithelial?mesenchymal transition via the inhibition of TGF-β and PI3K/AKT signaling pathways in triple-negative breast cancer cells.
Chen WC, et al.
Journal of Agricultural and Food Chemistry, 61.48, 11817-11824 (2013)
Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm
Lindsay ME, et al.
Nature Genetics, 44(8), 922?927-922?927 (201)
The immunopharmacological properties of transforming growth factor β.
Le Y, et al.
International Immunopharmacology, 13-14, 1771-1782 (2005)
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