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Showing 1-30 of 201 results for "WTA2" within Papers
Anna Sheveleva et al.
Virus genes, 47(2), 385-388 (2013-07-03)
The near-complete (99.7 %) genome sequence of a novel Russian Plum pox virus (PPV) isolate Pk, belonging to the strain Winona (W), has been determined by 454 pyrosequencing with the exception of the thirty-one 5'-terminal nucleotides. This region was amplified using
Ilya A Shestopalov et al.
Nature chemical biology, 8(3), 270-276 (2012-01-31)
Transcription factors have diverse roles during embryonic development, combinatorially controlling cellular states in a spatially and temporally defined manner. Resolving the dynamic transcriptional profiles that underlie these patterning processes is essential for understanding embryogenesis at the molecular level. Here we
John L Mokili et al.
PloS one, 8(3), e58404-e58404 (2013-04-05)
As part of a virus discovery investigation using a metagenomic approach, a highly divergent novel Human papillomavirus type was identified in pooled convenience nasal/oropharyngeal swab samples collected from patients with febrile respiratory illness. Phylogenetic analysis of the whole genome and
B A Benayoun et al.
Oncogene, 32(22), 2739-2746 (2012-07-17)
Ovarian granulosa cell tumors (OGCT) are the most frequent kind of sex cord-stromal tumors, and represent ∼2-5% of all ovarian malignancies. OGCTs exist as two entities, juvenile and adult types, with specific clinical and pathological characteristics. The molecular pathogenesis of
Kalyan C Chapalamadugu et al.
PloS one, 9(2), e89096-e89096 (2014-03-04)
Conditions during fetal development influence health and disease in adulthood, especially during critical windows of organogenesis. Fetal exposure to the endocrine disrupting chemical, bisphenol A (BPA) affects the development of multiple organ systems in rodents and monkeys. However, effects of
Xinghua Pan et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(2), 594-599 (2012-12-26)
The ability to determine the gene expression pattern in low quantities of cells or single cells is important for resolving a variety of problems in many biological disciplines. A robust description of the expression signature of a single cell requires
Adrian Reich et al.
The Journal of biological chemistry, 286(47), 40743-40749 (2011-09-29)
Improved methods are needed to reliably and accurately evaluate oocyte quality prior to fertilization and transfer into the woman of human embryos created through in vitro fertilization (IVF). All oocytes that are retrieved and matured in culture are exposed to
Omaththage P Perera et al.
PloS one, 10(6), e0128563-e0128563 (2015-06-06)
Heliothine pests such as the tobacco budworm, Heliothis virescens (F.), pose a significant threat to production of a variety of crops and ornamental plants and are models for developmental and physiological studies. The efforts to develop new control measures for
Meik Dilcher et al.
Virology, 423(1), 68-76 (2011-12-23)
We determined the complete genome sequences of Tribeč virus (TRBV) and Kemerovo virus (KEMV), two tick-transmitted Orbiviruses that can cause diseases of the central nervous system and that are currently classified into the Great Island virus serogroup. VP2 proteins of
Carolyn J Decker et al.
Cell reports, 7(3), 898-906 (2014-04-29)
Double-stranded RNA (dsRNA) can function as genetic information and may have served as genomic material before the existence of DNA-based life. By developing a method to purify dsRNA, we have investigated the diversity of dsRNA in microbial populations. We detect
Sarah A Dick et al.
Nature immunology, 20(1), 29-39 (2018-12-13)
Macrophages promote both injury and repair after myocardial infarction, but discriminating functions within mixed populations remains challenging. Here we used fate mapping, parabiosis and single-cell transcriptomics to demonstrate that at steady state, TIMD4+LYVE1+MHC-IIloCCR2- resident cardiac macrophages self-renew with negligible blood
Muhammad Farooq Rai et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 36(1), 484-497 (2017-07-28)
Microarrays and RNA-seq are at the forefront of high throughput transcriptome analyses. Since these methodologies are based on different principles, there are concerns about the concordance of data between the two techniques. The concordance of RNA-seq and microarrays for genome-wide
Sandra Klur et al.
Genomics, 83(3), 508-517 (2004-02-14)
Various approaches have been developed for the preparation of samples for gene expression monitoring. For Affymetrix chips, a standard protocol is widely used; however, this is inefficient for small samples such as laser capture microdissections. Several amplification procedures for such
Nair Olguín et al.
Food microbiology, 51, 87-95 (2015-07-19)
The correct development of malolactic fermentation depends on the capacity of Oenococcus oeni to survive under harsh wine conditions. The presence of ethanol is one of the most stressful factors affecting O. oeni performance. In this study, the effect of ethanol
Anne-Laure Vivant et al.
Applied and environmental microbiology, 81(15), 5073-5084 (2015-05-24)
In a recent paper, we demonstrated that inactivation of the Agr system affects the patterns of survival of Listeria monocytogenes (A.-L. Vivant, D. Garmyn, L. Gal, and P. Piveteau, Front Cell Infect Microbiol 4:160, In this study, we investigated
Corinne P Oechslin et al.
Frontiers in cellular and infection microbiology, 8, 375-375 (2018-11-09)
The etiologic cause of encephalitis, meningitis or meningo-encephalitis is unknown in up to 70% of cases. Clinical shotgun metagenomics combined with host depletion is a promising technique to identify infectious etiologies of central nervous system (CNS) infections. We developed a
Gaopeng Hou et al.
mBio, 12(6), e0320821-e0320821 (2021-12-15)
Rotavirus (RV)-encoded nonstructural protein 1 (NSP1), the product of gene segment 5, effectively antagonizes host interferon (IFN) signaling via multiple mechanisms. Recent studies with the newly established RV reverse genetics system indicate that NSP1 is not essential for the replication
Éva Korpos et al.
Diabetes, 62(2), 531-542 (2012-11-10)
We provide the first comprehensive analysis of the extracellular matrix (ECM) composition of peri-islet capsules, composed of the peri-islet basement membrane (BM) and subjacent interstitial matrix (IM), in development of type 1 diabetes in NOD mice and in human type
Nádia Conceição-Neto et al.
Virus evolution, 3(2), vex024-vex024 (2017-09-20)
Diarrhea outbreaks in pig farms have raised major concerns in Europe and USA, as they can lead to dramatic pig losses. During a suspected outbreak in Belgium of porcine epidemic diarrhea virus (PEDV), we performed viral metagenomics to assess other
Marion Claudia Salzer et al.
Cell, 175(6), 1575-1590 (2018-11-13)
During aging, stromal functions are thought to be impaired, but little is known whether this stems from changes of fibroblasts. Using population- and single-cell transcriptomics, as well as long-term lineage tracing, we studied whether murine dermal fibroblasts are altered during
Jelena Mirkovic et al.
The Journal of pathology, 236(3), 265-271 (2015-03-19)
Recent studies have suggested the involvement of a unique population of cells at the cervical squamo-columnar junction (SCJ) in the pathogenesis of early (squamous intraepithelial lesion or SIL) and advanced (squamous cell and adeno-carcinomas) cervical neoplasia. However, there is little
Michael C Risk et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 16(22), 5414-5423 (2010-10-12)
Several malignancies are known to exhibit a "field effect," whereby regions beyond tumor boundaries harbor histologic or molecular changes that are associated with cancer. We sought to determine if histologically benign prostate epithelium collected from men with prostate cancer exhibits
Christian Diniz Beduschi Travassos Alves et al.
Comparative immunology, microbiology and infectious diseases, 58, 36-43 (2018-09-25)
Astroviruses are a common cause of gastroenteritis in children worldwide and can also cause infection in a range of domestic and wild animal species. Canine astrovirus (formally named as Mamastrovirus 5, MAstV5) has been reported worldwide, and its role as
Mylarappa Ningappa et al.
PloS one, 10(9), e0138381-e0138381 (2015-09-18)
Altered extrahepatic bile ducts, gut, and cardiovascular anomalies constitute the variable phenotype of biliary atresia (BA). To identify potential susceptibility loci, Caucasian children, normal (controls) and with BA (cases) at two US centers were compared at >550000 SNP loci. Systems
Ahrin Huh et al.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 144(4), 568-576 (2013-10-01)
Genetic influences on the development of malocclusion include heritable effects on both masticatory muscles and jaw skeletal morphology. Beyond genetic variations, however, the characteristics of muscle and bone are also influenced by epigenetic mechanisms that produce differences in gene expression.
Comparative Metagenomics of Viral Assemblages Inhabiting Four Phyla of Marine Invertebrates
Gudenkauf, et al.
Frontiers in Marine Science, 3, 23-23 (2016)
Tiphaine Parrot et al.
Scientific reports, 10(1), 5900-5900 (2020-04-05)
Peripheral CD4+CD8+ double positive (DP) T cells are a phenotypically and functionally heterogeneous population depending on their origin and pathologic context. We previously identified among tumour infiltrating lymphocytes in melanoma, a tumour-reactive MHC class-I restricted CD4lowCD8high DP αβ T-cell subpopulation
Miguel Torres-Martin et al.
International journal of oncology, 42(3), 848-862 (2013-01-29)
Vestibular schwannomas are benign neoplasms that arise from the vestibular nerve. The hallmark of these tumors is the biallelic inactivation of neurofibromin 2 (NF2). Transcriptomic alterations, such as the neuregulin 1 (Nrg1)/ErbB2 pathway, have been described in schwannomas. In this
Youn Hee Nam et al.
Journal of ginseng research, 45(1), 183-190 (2021-01-14)
The circadian rhythm is the internal clock that controls sleep-wake cycles, metabolism, cognition, and several processes in the body, and its disruption has been associated with aging. The differentiated embryo chondrocyte (Dec) gene is related to circadian rhythm. To our
Ken Cadwell et al.
Cell, 141(7), 1135-1145 (2010-07-07)
It is unclear why disease occurs in only a small proportion of persons carrying common risk alleles of disease susceptibility genes. Here we demonstrate that an interaction between a specific virus infection and a mutation in the Crohn's disease susceptibility
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