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Showing 1-30 of 104 results for "Y0001259" within Papers
Sandra Burghoff et al.
BMC cancer, 14, 898-898 (2014-12-04)
Recent studies have suggested that adenosine generated by ecto-5'-nucleotidase (CD73) in the tumor microenvironment plays a major role in promoting tumor growth by suppressing the immune response and stimulating angiogenesis via A2A and A2B receptors. However, adenosine has also been
Elisabetta Giannessi et al.
Journal of reconstructive microsurgery, 30(9), 617-626 (2014-05-20)
The aim of this study was to investigate the ability of suturable platelet-rich plasma (PRP) membrane to promote peripheral nerve regeneration after neurotmesis and neurorraphy. A total of 36 rats were used: 32 animals underwent surgery and were split in
Brian T David et al.
Journal of neurotrauma, 31(21), 1800-1806 (2014-06-18)
Spinal cord injury (SCI) affects motor, sensory, and autonomic functions. As current therapies do not adequately alleviate functional deficits, the development of new and more effective approaches is of critical importance. Our earlier investigations indicated that intrathecal administration of a
Guyue Cheng et al.
Analytical and bioanalytical chemistry, 406(30), 7899-7910 (2014-10-31)
Fluoroquinolones (FQNs) are broad-spectrum antibacterial agents widely used in animal husbandry and aquaculture. The residues and antimicrobial resistance of such antibiotics are a major public health concern. To realize multianalyte detection of FQN residues, a genetically modified bacterium, Escherichia coli
Catherine Protogeraki et al.
European journal of medicinal chemistry, 86, 189-201 (2014-08-26)
The cobalt(II) complexes with the quinolone antimicrobial agent enrofloxacin (Herx) in the presence of the nitrogen-donor heterocyclic ligands pyridine (py), 2,2'-bipyridylamine (bipyam), 1,10-phenanthroline (phen), 2,2'-bipyridine (bipy) or the oxygen-donor ligand N,N-dimethylformamide (DMF) were synthesized and characterized. The crystal structures of
J P Liang et al.
Journal of veterinary pharmacology and therapeutics, 37(5), 508-514 (2014-03-13)
Accumulation and elimination of enrofloxacin and its metabolite ciprofloxacin were evaluated in Exopalaemon carinicauda following medicated feed at dose of 10 mg/kg weight body per day for five consecutive days and 10 mg/L bath for five consecutive days at 18 °C. At different
Alketa Tarushi et al.
Journal of inorganic biochemistry, 121, 53-65 (2013-01-29)
Interaction of equimolar quantities of ZnCl2 with the quinolone antibacterial drugs flumequine (Hflmq), oxolinic acid (Hoxo) or enrofloxacin (Herx) and the N,N'-donor heterocyclic ligands 1,10-phenanthroline (phen) or 2,2'-bipyridine (bipy) results in the formation of 1:1 drug to metal complexes with
Yu Bin Ho et al.
The Science of the total environment, 488-489, 261-267 (2014-05-20)
Repeated applications of animal manure as fertilizer are normal agricultural practices that may release veterinary antibiotics and hormones into the environment from treated animals. Broiler manure samples and their respective manure-amended agricultural soil samples were collected in selected locations in
D S Bayerl et al.
Journal of neuroendocrinology, 26(12), 918-926 (2014-10-07)
Maternal behaviour in rodents is mediated by the central oxytocin and vasopressin systems, amongst others. The role of vasopressin, acting via the V1a receptor (V1aR), on maternal care and maternal aggression has recently been described. However, a potential involvement of the
Rebecca J Henry et al.
Journal of neuroimmunology, 276(1-2), 126-134 (2014-09-24)
The present study examined the effect of enhancing fatty acid amide hydrolase (FAAH) substrate levels in vivo on Toll-like receptor (TLR)3-induced neuroinflammation. Systemic and central (i.c.v.) administration of the FAAH inhibitor URB597 increased hippocampal levels of the N-acylethanolamines palmitoylethanolamide and
Guntis Cepurnieks et al.
Journal of pharmaceutical and biomedical analysis, 102, 184-192 (2014-10-06)
A new multi-class method has been developed for the identification and quantification of the residues of 26 antibiotics from different classes (sulfonamides, macrolides, tetracyclines, penicillins, and quinolones) in milk and meat by ultra performance liquid chromatography coupled to hybrid quadrupole
Jochen Springer et al.
Stroke, 45(12), 3675-3683 (2014-10-30)
Muscle wasting is a common complication accompanying stroke. Although it is known to impair poststroke recovery, the mechanisms of subacute catabolism after stroke have not been investigated in detail. The aim of this study is to investigate mechanisms of local
Jennifer J Kilburn et al.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 42(3), 485-489 (2012-09-07)
A 32-year-old male Asian elephant (Elephas maximus) underwent routine transrectal stimulation for semen collection as part of an artificial insemination program. The procedure consisted of a preinsemination semen collection followed by two consecutive days of semen collections for artificial insemination.
Roxana A Stefanescu et al.
Journal of neurophysiology, 113(3), 956-970 (2014-11-14)
Tinnitus has been associated with enhanced central gain manifested by increased spontaneous activity and sound-evoked firing rates of principal neurons at various stations of the auditory pathway. Yet, the mechanisms leading to these modifications are not well understood. In a
Toyotaka Sato et al.
The Journal of veterinary medical science, 76(7), 937-945 (2014-03-22)
Understanding the prevalence of antimicrobial-resistance and the relationship between emergence of resistant bacteria and clinical treatment can facilitate design of effective treatment strategies. We here examined antimicrobial susceptibilities of Escherichia coli isolated from dogs admitted to a university hospital (University
Debbie Le Blon et al.
Immunology and cell biology, 92(8), 650-658 (2014-07-02)
Although implantation of cellular material in the central nervous system (CNS) is a key direction in CNS regenerative medicine, this approach is currently limited by the occurrence of strong endogenous immune cell responses. In a model of mesenchymal stem cell
Gwenaëlle Mourand et al.
Journal of medical microbiology, 63(Pt 11), 1552-1560 (2014-08-22)
An experiment was conducted to compare the impact of antimicrobial treatments on the susceptibility of Campylobacter, Enterococcus faecium and Enterococcus faecalis, and on the diversity of broiler microbiota. Specific-pathogen-free chickens were first orally inoculated with strains of Campylobacter and Enterococcus
Seung Ryul Han et al.
Biochemical and biophysical research communications, 448(4), 397-402 (2014-05-06)
Danofloxacin is a synthetic fluoroquinolone with broad spectrum antibacterial activity that is used for the treatment of respiratory diseases in animal husbandry. However, danofloxacin has many adverse reactions and is toxic to humans. Especially, it detrimentally affects muscle, central nerve
Darryl R Overby et al.
Investigative ophthalmology & visual science, 55(8), 4922-4933 (2014-07-17)
To determine whether dexamethasone (DEX)-induced ocular hypertension (OHT) in mice mimics the hallmarks of steroid-induced glaucoma (SIG) in humans, including reduced conventional outflow facility (C), increased extracellular matrix (ECM), and myofibroblasts within the outflow pathway. Osmotic mini-pumps were implanted subcutaneously
Yisheng Chen et al.
Journal of chromatography. A, 1356, 249-257 (2014-07-13)
The world-wide usage and partly abuse of veterinary antibiotics resulted in a pressing need to control residues in animal-derived foods. Large-scale screening for residues of antibiotics is typically performed by microbial agar diffusion tests. This work employing high-performance thin-layer chromatography
Leigh V Panlilio et al.
Psychopharmacology, 232(8), 1451-1460 (2014-11-05)
Animal models that allow concurrent access to drug and nondrug reinforcers provide unique insight into the etiology, maintenance, and treatment of drug use. We sought to develop and utilize a concurrent access procedure with nicotine and sucrose in rats. Pressing
Paul D Rainville et al.
The Analyst, 140(6), 1921-1931 (2015-02-07)
The emergence of micro sampling techniques holds great potential to improve pharmacokinetic data quality, reduce animal usage, and save costs in safety assessment studies. The analysis of these samples presents new challenges for bioanalytical scientists, both in terms of sample
David J Durgan et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 35(3), 402-411 (2014-11-27)
Obstructive sleep apnea (OSA) is associated with cerebrovascular diseases. However, little is known regarding the effects of OSA on the cerebrovascular wall. We tested the hypothesis that OSA augments endothelin-1 (ET-1) constrictions of cerebral arteries. Repeated apneas (30 or 60
J T Howard et al.
Journal of veterinary pharmacology and therapeutics, 37(6), 531-541 (2014-04-16)
Drug use in livestock has received increased attention due to welfare concerns and food safety. Characterizing heterogeneity in the way swine populations respond to drugs could allow for group-specific dose or drug recommendations. Our objective was to determine whether drug
Michael Lukas et al.
Journal of neuroscience methods, 234, 101-107 (2014-04-09)
Research concerning non-reproductive sociability in rodents is mainly restricted to assessing the effects of oxytocin (OXT) and arginine-vasopressin (AVP) in male rats and mice. Comparable studies on natural social preference and social avoidance in females are substantially lacking. Here, we
Xiaoning Lei et al.
Environmental science and pollution research international, 22(3), 1670-1678 (2014-05-09)
This study investigated the residues of four sulfonamides, four quinolones, and four tetracyclines in surface water as well as surficial sediment samples, of Bosten Lake, in Xinjiang, China. The results showed the presence of 10 out of the 12 selected
E M Swartz et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 26(12), 1717-1729 (2014-10-16)
Clinical reports indicate that spinal cord injury (SCI) initiates profound gastric dysfunction. Gastric reflexes involve stimulation of sensory vagal fibers, which engage brainstem circuits that modulate efferent output back to the stomach, thereby completing the vago-vagal reflex. Our recent studies
Maria Bobu et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 48(3), 251-262 (2012-12-19)
In this study a comparative assessment using various advanced oxidation processes (UV/H(2)O(2), UV/H(2)O(2)/Fe(II), O(3), O(3)/UV, O(3)/UV/H(2)O(2) and O(3)/UV/H(2)O(2)/Fe(II)) was attempted to degrade efficiently two fluoroquinolone drugs ENR [enrofloxacin (1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolonecarboxylic acid)] and CIP [ciprofloxacin (1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-quinoline-3-carboxylic acid)] in aqueous solutions at a
M Cengiz et al.
The Veterinary record, 172(18), 474-474 (2013-04-23)
The objective of this work was to investigate the bactericidal activity of enrofloxacin against gyrA mutant and qnr-containing Escherichia coli isolates from animals. The minimum inhibitory concentrations (MICs) of gyrA mutant and qnr-containing E coli isolates ranged from 1 µg/ml
S C Coelho et al.
European journal of pain (London, England), 18(7), 957-967 (2014-01-09)
This study evaluated the involvement of tumour necrosis factor α (TNF-α) in orofacial thermal and mechanical hyperalgesia induced by an inflammatory stimulus or by chronic constriction of the infraorbital nerve (CION) using etanercept (Eta), a TNF-receptor fusion protein that inhibits
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