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SB 225002 A potent, selective, and competitive antagonist of the G-protein coupled receptor CXCR2 (IL-8RB; IC₅₀ = 22 nM for the inhibition of ¹²⁵I-IL-8 binding to CXCR2).

SB225002

SB 225002 A potent, selective, and competitive antagonist of the G-protein coupled receptor CXCR2 (IL-8RB; IC₅₀ = 22 nM for the inhibition of ¹²⁵I-IL-8 binding to CXCR2).

Synonym(s):

N-(2-Hydroxy-4-nitrophenyl)-N′-(2-bromophenyl)urea, SB-225002, SB 225002

Empirical Formula (Hill Notation):

C₁₃H₁₀BrN₃O₄

CAS Number:

Molecular Weight:

352.14

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bioactive small molecules (2)

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SML0716

SB225002, ≥98% (HPLC)

559405

SB225002, A potent, selective, and competitive antagonist of the G-protein coupled receptor CXCR2 (IL-8RB; IC₅₀ = 22 nM for the inhibition of ¹²⁵I-IL-8 binding to CXCR2).