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  • Aristapedioid: a gain of function, homeotic mutation in Drosophila melanogaster.

Aristapedioid: a gain of function, homeotic mutation in Drosophila melanogaster.

Genetics (1990-01-01)
B P Brunk, P N Adler
ABSTRACT

The isolation of gain of function mutations has allowed the identification of a number of genes which are important in the normal development of the organism. We report here the isolation and characterization of Aristapedioid, a gain of function mutation which causes a partial transformation of arista towards tarsus and the loss or decrease in size of the dorso-central and scutellar bristles. Aristapedioid is the result of a P element mediated inversion which juxtaposes unrelated DNA adjacent to Suppressor 2 of zeste, causing a gain of function mutation in that gene.

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Sephadex® G-50, Fine