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  • Synthesis and reduction kinetics of sterically shielded pyrrolidine nitroxides.

Synthesis and reduction kinetics of sterically shielded pyrrolidine nitroxides.

Organic letters (2012-10-12)
Joseph T Paletta, Maren Pink, Bridget Foley, Suchada Rajca, Andrzej Rajca
ABSTRACT

A series of sterically shielded pyrrolidine nitroxides were synthesized, and their reduction by ascorbate (vitamin C) indicate that nitroxide 3, a tetraethyl derivative of 3-carboxy-PROXYL, is reduced at the slowest rate among known nitroxides, i.e., at a 60-fold slower rate than that for 3-carboxy-PROXYL.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Pyrrolidine, ≥99.5%, purified by redistillation
Sigma-Aldrich
Pyrrolidine, ≥99.0%
Sigma-Aldrich
Pyrrolidine, FG
Sigma-Aldrich
Pyrrolidine, 99%