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  • Hopanoids are formed during transition from substrate to aerial hyphae in Streptomyces coelicolor A3(2).

Hopanoids are formed during transition from substrate to aerial hyphae in Streptomyces coelicolor A3(2).

FEMS microbiology letters (2000-07-29)
K Poralla, G Muth, T Härtner
ABSTRACT

Streptomyces coelicolor A3(2) contains a cluster of putative isoprenoid and hopanoid biosynthetic genes. The strain does not produce the pentacyclic hopanoids in liquid culture but produces them on solid medium when sporulating. Mutants defective in the formation of aerial mycelium and spores (bld), with the exception of bldB, do not synthesize hopanoids, whereas mutants, which form aerial mycelium but no spores (whi), do. The membrane condensing hopanoids possibly may alleviate stress in aerial mycelium by diminishing water permeability across the membrane.

MATERIALS
Product Number
Brand
Product Description

Supelco
Hop-22(29)-ene solution, 0.1 mg/mL in isooctane, analytical standard