MilliporeSigma

Profound insights into squalene cyclization.

Chemistry & biology (2004-04-29)
Karl Poralla
ABSTRACT

In this issue of Chemistry & Biology, our understanding of the formation of pentacyclic hopene from the linear squalene is enhanced by an X-ray structure of a complex between squalene-hopene cyclase and the substrate analog 2-azasqualene.

MATERIALS
Product Number
Brand
Product Description

Supelco
Hop-22(29)-ene solution, 0.1 mg/mL in isooctane, analytical standard
Supelco
Squalene, analytical standard
Sigma-Aldrich
Squalene, ≥98%, liquid