MilliporeSigma

Fragrance contact dermatitis in Korea: a joint study.

Contact dermatitis (2005-12-21)
Susun An, Ai-Young Lee, Cheol Heon Lee, Do-Won Kim, Jeong Hee Hahm, Kea-Jeung Kim, Kee-Chan Moon, Young Ho Won, Young-Suck Ro, Hee Chul Eun
ABSTRACT

The purpose of this study is to determine the frequency of responses to selected fragrances in patients with suspected fragrance allergy and to evaluate the risk factors. 9 dermatology departments of university hospitals have participated in this study for the past 1 year. To determine allergic response to fragrances, 18 additional fragrances in addition to the Korean standard and a commercial fragrance series were patch-tested in patients with suspecting cosmetic contact dermatitis. Over 80% of the patients were women, and the most common site was the face. Cinnamic alcohol and sandalwood oil (Santalum album L.) showed high frequencies of positive responses. Of the specific fragrances, ebanol, alpha-isomethyl-ionone (methyl ionone-gamma) and Lyral (hydroxyisohexyl 3-cyclohexane carboxdaldehyde) showed high positive responses. We compared the results obtained during this study with those of other studies and concluded that including additional fragrance allergens may be useful for the detection of fragrance allergy.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
α-Cetone, odorant used in allergy studies
Sigma-Aldrich
Sandalwood oil, natural