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  • Optimization of radiation therapy techniques for prostate cancer with prostate-rectum spacers: a systematic review.

Optimization of radiation therapy techniques for prostate cancer with prostate-rectum spacers: a systematic review.

International journal of radiation oncology, biology, physics (2014-10-12)
Gary Mok, Eileen Benz, Jean-Paul Vallee, Raymond Miralbell, Thomas Zilli
ABSTRACT

Dose-escalated radiation therapy for localized prostate cancer improves disease control but is also associated with worse rectal toxicity. A spacer placed between the prostate and rectum can be used to displace the anterior rectal wall outside of the high-dose radiation regions and potentially minimize radiation-induced rectal toxicity. This systematic review focuses on the published data regarding the different types of commercially available prostate-rectum spacers. Dosimetric results and preliminary clinical data using prostate-rectum spacers in patients with localized prostate cancer treated by curative radiation therapy are compared and discussed.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Hyaluronic acid sodium salt from Streptococcus equi, mol wt 130,000-150,000
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Hyaluronic acid sodium salt from Streptococcus equi, mol wt 90,000-110,000
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Hyaluronic acid sodium salt from Streptococcus equi, mol wt 750,000-1,000,000
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Hyaluronic acid sodium salt from Streptococcus equi, mol wt 1,750,000-2,000,000
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Hyaluronic acid sodium salt from Streptococcus equi, mol wt 300,000-500,000
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Collagen Type IV from human cell culture, Bornstein and Traub Type IV, 0.3 mg/mL, sterile-filtered, BioReagent, suitable for cell culture
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Hyaluronic acid sodium salt from Streptococcus equi, mol wt 120,000-350,000
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Hyaluronic acid sodium salt from Streptococcus equi, mol wt 70,000-120,000
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Hyaluronic acid sodium salt from Streptococcus equi, mol wt 50,000-70,000
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