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  • A Versatile Synthetic Extracellular Matrix Mimic via Thiol-Norbornene Photopolymerization.

A Versatile Synthetic Extracellular Matrix Mimic via Thiol-Norbornene Photopolymerization.

Advanced materials (Deerfield Beach, Fla.) (2009-12-28)
Benjamin D Fairbanks, Michael P Schwartz, Alexandra E Halevi, Charles R Nuttelman, Christopher N Bowman, Kristi S Anseth
ABSTRACT

Step-growth, radically mediated thiol-norbornene photopolymerization is used to create versatile, stimuli-responsive poly(ethylene glycol)-co-peptide hydrogels The reaction is cytocompatible and allows for the encapsulation of human mesenchymal stem cells with a viability greater than 95%. Cellular spreading is dictated via three-dimensional biochemical photopatterning.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
5-Norbornene-2-carboxylic acid, mixture of endo and exo, predominantly endo, 98%