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Highly oxygenated sesquiterpenes in Artemisia alba Turra.

Phytochemistry (2014-12-30)
Milka Todorova, Antoaneta Trendafilova, Kalina Danova, Luke Simmons, Evelyn Wolfram, Beat Meier, Rainer Riedl, Luba Evstatieva
ABSTRACT

Ten new sesquiterpene alcohols of which seven germacranes, a eudesmane, a guaiane and an oplopane were isolated from the aerial parts of Artemisia alba Turra. Their structures and relative stereochemistry were elucidated by spectral methods ((1)H and (13)C NMR, COSY, HSQC, HMBC, NOESY, and MS). In addition, the known 7-hydroxycadin-4-en-3-one, centaureidin and axillarin were found for the first time in the studied species.

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