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Red yeast rice repairs kidney damage and reduces inflammatory transcription factors in rat models of hyperlipidemia.

Red yeast rice repairs kidney damage and reduces inflammatory transcription factors in rat models of hyperlipidemia.

Experimental and therapeutic medicine (2014-11-06)

Mei Ding, Daoyuan Si, Wenqi Zhang, Zhaohui Feng, Min He, Ping Yang

ABSTRACT

Xuezhikang (XZK), an extract of red yeast rice, has been widely used for the management of hyperlipidemia and coronary heart disease (CHD); however, the effects of XZK treatment on kidney injury have not yet been fully identified. The aim of the current study was to evaluate the effects of XZK on the kidneys and investigate the related mechanisms in a rat model of hyperlipidemia. Thus, the effect on inflammatory transcription factors and kidney damage was investigated with

MATERIALS

Product Number

Brand

Product Description

Sigma-Aldrich

3,3′,5,5′-Tetramethylbenzidine, ≥98.0% (NT)

Supelco

3,3′,5,5′-Tetramethylbenzidine, standard for GC

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SyntheChol^® NS0 Supplement, 500 ×, synthetic cholesterol, animal component-free, aqueous solution, sterile-filtered, suitable for cell culture

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3,3′,5,5′-Tetramethylbenzidine, ≥99%

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3,3′,5,5′-Tetramethylbenzidine, tablet, 1 mg substrate per tablet

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Cholecalciferol, meets USP testing specifications

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Cholesterol, powder, BioReagent, suitable for cell culture, ≥99%

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Cholesterol, Sigma Grade, ≥99%

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Cholecalciferol, ≥98% (HPLC)

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3,3′,5,5′-Tetramethylbenzidine, ≥98% (TLC)

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4,4′-Diaminodiphenylmethane, ≥97.0% (GC)

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USP

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SAFC

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