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  • Synergistic Catalysis by "Polymeric Microzymes and Inorganic Nanozymes": The 1+1>2 Effect for Intramolecular Cyclization of Peptides.

Synergistic Catalysis by "Polymeric Microzymes and Inorganic Nanozymes": The 1+1>2 Effect for Intramolecular Cyclization of Peptides.

Frontiers in chemistry (2017-10-12)
Zhiliang Chen, Börje Sellergren, Xiantao Shen
ABSTRACT

In this work, we developed an efficient "molecularly imprinted polymer microzymes and inorganic magnetic nanozymes" synergistic catalysis strategy for the formation of disulfide bonds in peptides. The polymeric microzymes showed excellent selectivity toward the template peptide as well as the main reactant (linear peptide), and the Fe

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
[deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate, ≥95% (HPLC)
Sigma-Aldrich
N-tert-Butylacrylamide, 97%