Skip to Content
MilliporeSigma

HPLC Analysis of Protein Standards on Zenix® SEC-300 using Different Buffer Systems

HPLC Analysis of Protein Standards on Zenix® SEC-300 using Different Buffer Systems application for HPLC

Materials

Analytical column

Product No.
Description
Pricing

Zenix® SEC-300 Gel Filtration Column, 3 μm

L × I.D. 30 cm × 4.6 mm, 3 μm particle size, stainless steel

mobile phase component

Product No.
Description
Pricing

Ammonium bicarbonate

BioUltra, ≥99.5% (T)

standard

Product No.
Description
Pricing

Myoglobin from equine heart

≥90% (SDS-PAGE), essentially salt-free, lyophilized powder

Uracil

≥99.0%

Thyroglobulin from bovine thyroid

(For Gel Filtration Chromatography)

IgG from rabbit serum

reagent grade, ≥95% (SDS-PAGE), essentially salt-free, lyophilized powder

Bovine Serum Albumin

lyophilized powder, ≥96% (agarose gel electrophoresis)

CONDITIONS

column

Zenix SEC-300, 30 cm x 4.6 mm I.D., 3 μm particles (Z777028)

mobile phase

[A] 0.15 M potassium phosphate monobasic, pH 7.0 with phosphoric acid; [B] 0.1 M ammonium bicarbonate (pH unadjusted)

flow rate

0.3 mL/min

column temp.

25 °C

detector

UV, 280 nm

detector

1000 psi

injection

2.5 μL

sample

in mobile phase

Description

Analysis Note

This application compares selectivity of proteins when chromotographed by size exclusion with different buffer systems.

Legal Information

Zenix is a registered trademark of Sepax Technologies