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AKT2

v-akt murine thymoma viral oncogene homolog 2

Synonyms:
HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA
Species:
UniProtKB ID:
Gene ID:
  • Human(208) Summary: This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]
  • Mouse(11652) thymoma viral proto-oncogene 2
  • Rat(25233) v-akt murine thymoma viral oncogene homolog 2
  • chicken(373973) v-akt murine thymoma viral oncogene homolog 2
  • domestic guinea pig(100719925) v-akt murine thymoma viral oncogene homolog 2
  • naked mole-rat(101719164) v-akt murine thymoma viral oncogene homolog 2
  • cow(534923) v-akt murine thymoma viral oncogene homolog 2
  • Horse(100064671) v-akt murine thymoma viral oncogene homolog 2
  • sheep(101119242) v-akt murine thymoma viral oncogene homolog 2
  • Zebrafish(378972) v-akt murine thymoma viral oncogene homolog 2
  • domestic cat(100499544) v-akt murine thymoma viral oncogene homolog 2
  • dog(449021) v-akt murine thymoma viral oncogene homolog 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-AKT2 (pSer474) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-AKT2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-AKT2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
Anti-Phospho-AKT2-S474 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti- AKT2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot

Cell Lines

Product Number
Description
Species
DLD1 CELLS AKT2 -/-, ,
Species
human
MCF10A CELLS AKT2 (-/-), ,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
GSK690693, ≥98% (HPLC),
Species
human

Proteins

Product Number
Description
Species
AKT2, active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
SILuProt AKT2, RAC-beta serine/threonine-protein kinase human, recombinant, expressed in HEK 293 cells, 13C and 15N-labeled, SIL MS Protein Standard,
Species
human
SILuLite AKT2, RAC-beta serine/threonine-protein kinase human, recombinant, expressed in HEK 293 cells, MS Protein Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human AKT2,
Species
human
MISSION® esiRNA, targeting mouse Akt2,
Species
mouse