ANXA7
annexin A7
Synonyms:
ANX7, SNX, SYNEXIN
Species:
Human ANXA7 (310), Mouse Anxa7 (11750), Rat Anxa7 (155423), cow ANXA7 (533360), dog ANXA7 (479246), naked mole-rat Anxa7 (101707202), domestic guinea pig Anxa7 (100718696), chicken ANXA7 (423747), sheep ANXA7 (101118663), domestic cat ANXA7 (101085922)
UniProtKB ID:
Gene ID:
- Human(310) Summary: Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq, Jul 2008]
- Mouse(11750) annexin A7
- Rat(155423) annexin A7
- cow(533360) annexin A7
- dog(479246) annexin A7
- naked mole-rat(101707202) annexin A7
- domestic guinea pig(100718696) annexin A7
- chicken(423747) annexin A7
- sheep(101118663) annexin A7
- domestic cat(101085922) annexin A7
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ANXA7 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, rat
Application
western blot
Anti-ANXA7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-Annexin VII antibody, Mouse monoclonal, clone 203-217/6, purified from hybridoma cell culture,
Species Reactivity
bovine, canine, chicken, human, mouse, rabbit, rat
Application
immunocytochemistry
immunohistochemistry
microarray
western blot
immunohistochemistry
microarray
western blot