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ASGR2

asialoglycoprotein receptor 2

Synonyms:
ASGP-R2, ASGPR2, CLEC4H2, HBXBP, HL-2
Species:
UniProtKB ID:
Gene ID:
  • Human(433) Summary: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
  • Mouse(11890) asialoglycoprotein receptor 2
  • Rat(29403) asialoglycoprotein receptor 2
  • sheep(101115381) asialoglycoprotein receptor 2
  • naked mole-rat(101705711) asialoglycoprotein receptor 2
  • cow(531519) asialoglycoprotein receptor 2
  • domestic cat(101095292) asialoglycoprotein receptor 2
  • dog(100687999) asialoglycoprotein receptor 2
  • domestic guinea pig(100714463) asialoglycoprotein receptor 2

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ASGR2 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ASGR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ASGR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-ASGR2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-ASGPR sH2a Antibody, clone B9, ,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ASGR2,
Species
human
MISSION® esiRNA, targeting mouse Asgr2,
Species
mouse