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BAD

BCL2-associated agonist of cell death

Synonyms:
BBC2, BCL2L8
Species:
Human BAD (572), Mouse Bad (12015), Rat Bad (64639), dog BAD (483763), domestic cat BAD (768269), sheep BAD (780444), cow BAD (615013), naked mole-rat Bad (101726042), domestic guinea pig Bad (100734151)
UniProtKB ID:
Q92934, O14803, Q6FH21
Gene ID:
  • Human(572) Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(12015) BCL2-associated agonist of cell death
  • Rat(64639) BCL2-associated agonist of cell death
  • dog(483763) BCL2-associated agonist of cell death
  • domestic cat(768269) BCL2-associated agonist of cell death
  • sheep(780444) BCL2-associated agonist of cell death
  • cow(615013) BCL2-associated agonist of cell death
  • naked mole-rat(101726042) BCL2-associated agonist of cell death
  • domestic guinea pig(100734151) BCL2-associated agonist of cell death

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Small Molecule - Antagonist

Product Number
Description
Species
196487
4-Biphenylacetic acid, 98%,
Species
human
37760
2,3-Dihydroxynaphthalene, ≥98.0% (HPLC),
Species
human
B34729
Biphenyl-4-carboxylic acid, 95%,
Species
human
G8761
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB4502465
Anti-BAD antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
SAB4502466
Anti-BAD antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
SAB4502468
Anti-BAD antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
SAB3500336
Anti-BAD antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB4504345
Anti-phospho-BAD (pSer112) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SRP5164
BAD, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
EHU077271
MISSION® esiRNA, targeting human BAD,
Species
human