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Merck

CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

Sinónimos:
CACNA1HB, Cav3.2, ECA6, EIG6
Especie:
ID UniProtKB:
ID del gen:
  • Human(8912) Summary: This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008]
  • Mouse(58226) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • Rat(114862) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • dog(403533) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic cat(101090071) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic guinea pig(100720102) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • naked mole-rat(101712631) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • chicken(416526) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • cow(282412) calcium channel, voltage-dependent, T type, alpha 1H subunit

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

Número de producto
Descripción
Especie
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Cav3.2 Antibody, Chemicon®, from rabbit,
Reactividad de especies
rat
Aplicación
western blot

Small Molecule - Blocker

Número de producto
Descripción
Especie
Trimethadione, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Ethosuximide, British Pharmacopoeia (BP) Reference Standard,
Especie
human
Bepridil hydrochloride, powder,
Especie
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
Especie
human