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CACNB2

calcium channel, voltage-dependent, beta 2 subunit

Synonyms:
CACNLB2, CAVB2, MYSB
Species:
UniProtKB ID:
Gene ID:
  • Human(783) Summary: This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013]
  • Mouse(12296) calcium channel, voltage-dependent, beta 2 subunit
  • Rat(116600) calcium channel, voltage-dependent, beta 2 subunit
  • domestic guinea pig(100192393) calcium channel, voltage-dependent, beta 2 subunit
  • naked mole-rat(101713647) calcium channel, voltage-dependent, beta 2 subunit
  • Domestic Rabbit(100009277) calcium channel, voltage-dependent, beta 2 subunit
  • cow(327667) calcium channel, voltage-dependent, beta 2 subunit
  • sheep(101112498) calcium channel, voltage-dependent, beta 2 subunit
  • dog(487113) calcium channel, voltage-dependent, beta 2 subunit
  • domestic cat(101093028) calcium channel, voltage-dependent, beta 2 subunit
  • Horse(100055971) calcium channel, voltage-dependent, beta 2 subunit
  • chicken(428420) calcium channel, voltage-dependent, beta 2 subunit

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Small Molecule - Allosteric Modulator

Product Number
Description
Species
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Species
human
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Gabapentin solution, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CACNB2 antibody produced in mouse, clone 6C4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
western blot
Monoclonal Anti-CACNB2 antibody produced in mouse, clone 6C1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Monoclonal Anti-CACNB2 antibody produced in mouse, clone S8B-1, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Calcium Channel β 2 Antibody, near CT, Chemicon®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-CACNB2 (ab1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot

Small Molecule - Blocker

Product Number
Description
Species
Bepridil hydrochloride, powder,
Species
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CACNB2,
Species
human
MISSION® esiRNA, targeting mouse Cacnb2,
Species
mouse