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CDKN3

cyclin-dependent kinase inhibitor 3

Synonyms:
CDI1, CIP2, KAP, KAP1
Species:
UniProtKB ID:
Gene ID:
  • Human(1033) Summary: The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(72391) cyclin-dependent kinase inhibitor 3
  • Rat(289993) cyclin-dependent kinase inhibitor 3
  • dog(609346) cyclin-dependent kinase inhibitor 3
  • sheep(101116234) cyclin-dependent kinase inhibitor 3
  • chicken(423562) cyclin-dependent kinase inhibitor 3
  • cow(615282) cyclin-dependent kinase inhibitor 3
  • domestic guinea pig(100731849) cyclin-dependent kinase inhibitor 3
  • Zebrafish(402796) cyclin-dependent kinase inhibitor 3
  • naked mole-rat(101710612) cyclin-dependent kinase inhibitor 3
  • domestic cat(101100571) cyclin-dependent kinase inhibitor 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CDKN3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-CDKN3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

Small Molecule - Inhibitor

Product Number
Description
Species
Roscovitine, ≥98% (TLC),
Species
human, mouse, rat
Olomoucine, ≥98% (HPLC),
Species
human, rat

Proteins

Product Number
Description
Species
CDKN3, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CDKN3,
Species
human
MISSION® esiRNA, targeting mouse Cdkn3,
Species
mouse