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CFTR

cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)

Synonyms:
ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1
Species:
Human CFTR (1080), Mouse Cftr (12638), Rat Cftr (24255), domestic cat CFTR (492308), dog CFTR (492302), chicken CFTR (100049619), Zebrafish cftr (559080), Domestic Rabbit CFTR (100009471), sheep CFTR (443347), cow CFTR (281067) ...More
UniProtKB ID:
P13569, Q20BG8, Q20BH2, Q2I0A1, Q2I102
Gene ID:
  • Human(1080) Summary: This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12638) cystic fibrosis transmembrane conductance regulator
  • Rat(24255) cystic fibrosis transmembrane conductance regulator
  • domestic cat(492308) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  • dog(492302) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  • chicken(100049619) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  • Zebrafish(559080) cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)
  • Domestic Rabbit(100009471) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  • sheep(443347) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  • cow(281067) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  • Horse(100071259) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  • naked mole-rat(101709472) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  • domestic guinea pig(100135647) cystic fibrosis transmembrane conductance regulator homolog
  • domestic guinea pig(100719898) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
MAB3482
Anti-Cystic Fibrosis Transmembrane Conductance Regulator Antibody, clone MM13-4, clone MM13-4, Chemicon®, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
05-581
Anti-CFTR Antibody, clone MM13-4, clone MM13-4, Upstate®, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
MAB3484
Anti-Cystic Fibrosis Transmembrane Conductance Regulator Antibody, a.a. 386-412, clone L12B4, clone L12B4, Chemicon®, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
SAB4501942
Anti-CFTR antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
05-583
Anti-CFTR Antibody, clone M3A7, clone M3A7, Upstate®, from mouse,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)
western blot

esiRNA

Product Number
Description
Species
EHU020491
MISSION® esiRNA, targeting human CFTR,
Species
human
EMU012551
MISSION® esiRNA, targeting mouse Cftr,
Species
mouse