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CYP2C8

cytochrome P450, family 2, subfamily C, polypeptide 8

Synonyms:
CPC8, CYPIIC8, MP-12/MP-20
Species:
Human CYP2C8 (1558)
UniProtKB ID:
P10632, A8K9N8, B0AZN2, B7Z1F6, Q5VX93, Q8WWB1, Q9UCZ9
Gene ID:
  • Human(1558) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4500589
Anti-Cytochrome P450 2C8 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
HPA013547
Anti-CYP2C8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
SAB2501735
Anti-CYP2C8 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
HPA013970
Anti-CYP2C8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
T9652
Terfenadine, ,
Species
mouse, rat, human

esiRNA

Product Number
Description
Species
EHU068961
MISSION® esiRNA, targeting human CYP2C8,
Species
human