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Merck

GABRD

gamma-aminobutyric acid (GABA) A receptor, delta

Synonyma:
EIG10, EJM7, GEFSP5
Druh:
ID sady UniProtKB:
ID genu:
  • Human(2563) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(14403) gamma-aminobutyric acid (GABA) A receptor, subunit delta
  • Rat(29689) gamma-aminobutyric acid (GABA) A receptor, delta
  • Zebrafish(571422) gamma-aminobutyric acid (GABA) A receptor, delta
  • chicken(770710) gamma-aminobutyric acid (GABA) A receptor, delta
  • cow(508711) gamma-aminobutyric acid (GABA) A receptor, delta
  • dog(489609) gamma-aminobutyric acid (GABA) A receptor, delta
  • sheep(101122539) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic cat(101087589) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic guinea pig(100735228) gamma-aminobutyric acid (GABA) A receptor, delta
  • naked mole-rat(101700143) gamma-aminobutyric acid (GABA) A receptor, delta

Custom & Knockdown Gene Products

Small Molecule - Agonist

Číslo produktu
Popis
Druh
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Druh
human

Small Molecule - Allosteric Modulator

Číslo produktu
Popis
Druh
Oxazepam for peak identification, European Pharmacopoeia (EP) Reference Standard,
Druh
human
Triazolam, European Pharmacopoeia (EP) Reference Standard,
Druh
human
Lorazepam for system suitability, European Pharmacopoeia (EP) Reference Standard,
Druh
human
Midazolam maleate salt, ,
Druh
human
Estazolam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Druh
human

Small Molecule - Antagonist

Číslo produktu
Popis
Druh
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Druh
human
2,6-Diisopropylphenol, 97%,
Druh
human
Flumazenil, >99% (HPLC), solid,
Druh
rat, human
Acamprosate calcium, ≥98% (HPLC), powder,
Druh
human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Druh
human

Antibodies

Číslo produktu
Popis
Druhová reaktivita
Aplikace
Anti-GABRD antibody produced in rabbit, affinity isolated antibody,
Druhová reaktivita
bovine, dog, human, mouse, rabbit
Aplikace
immunohistochemistry
western blot
Anti-GABRD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Druhová reaktivita
human
Aplikace
immunohistochemistry

esiRNA

Číslo produktu
Popis
Druh
MISSION® esiRNA, targeting human GABRD,
Druh
human
MISSION® esiRNA, targeting mouse Gabrd,
Druh
mouse