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Merck

IL7

interleukin 7

Synonymes:
IL-7
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3574) Summary: The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010]
  • Mouse(16196) interleukin 7
  • Rat(25647) interleukin 7
  • chicken(420193) interleukin 7
  • dog(751768) interleukin 7
  • domestic cat(101084597) interleukin 7
  • cow(280827) interleukin 7
  • sheep(443341) interleukin 7
  • domestic guinea pig(100725811) interleukin 7
  • naked mole-rat(101713773) interleukin 7

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human IL-7 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human
Mouse IL-7 ELISA Kit, for serum, plasma and cell culture supernatant,
Espèce(s)
mouse

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Monoclonal Anti-IL7 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL11132, purified antibody (Protein A),
Espèces réactives
human
Application
immunofluorescence
Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1, clone 7B1.1, from mouse,
Espèces réactives
human
Application
flow cytometry
western blot
Anti-IL7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry

Proteins

Numéro du produit
Description
Espèce(s)
IL-7 human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Espèce(s)
human
Interleukin-7 human, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Espèce(s)
human
Interleukin-7 from mouse, ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Espèce(s)
mouse
IL-7 from rat, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espèce(s)
rat

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human IL7,
Espèce(s)
human