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IRF3

interferon regulatory factor 3

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(3661) Summary: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(54131) interferon regulatory factor 3
  • Rat(292892) interferon regulatory factor 3
  • domestic guinea pig(100724910) interferon regulatory factor 3
  • sheep(780485) interferon regulatory factor 3
  • cow(516979) interferon regulatory factor 3
  • domestic cat(101095934) interferon regulatory factor 3
  • naked mole-rat(101722762) interferon regulatory factor 3
  • Zebrafish(564854) interferon regulatory factor 3
  • dog(476412) interferon regulatory factor 3

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-IRF3 antibody produced in mouse, clone 3C8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunoprecipitation (IP)

western blot
Anti-Phospho-IRF3-S396 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-IRF3 Antibody, clone SL-12, clone SL-12, from mouse,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-phospho-IRF-3 (pSer386) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-phospho-IRF-3 (pSer386) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IRF3,
Species
human