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PAM

peptidylglycine alpha-amidating monooxygenase

Synonyms:
PAL, PHM
Species:
UniProtKB ID:
Gene ID:
  • Human(5066) Summary: This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known. [provided by RefSeq, Jul 2008]
  • Mouse(18484) peptidylglycine alpha-amidating monooxygenase
  • Rat(25508) peptidylglycine alpha-amidating monooxygenase
  • Zebrafish(570822) peptidylglycine alpha-amidating monooxygenase
  • chicken(427274) peptidylglycine alpha-amidating monooxygenase
  • dog(479145) peptidylglycine alpha-amidating monooxygenase
  • domestic cat(101084598) peptidylglycine alpha-amidating monooxygenase
  • Horse(791244) peptidylglycine alpha-amidating monooxygenase
  • cow(280890) peptidylglycine alpha-amidating monooxygenase
  • sheep(101112815) peptidylglycine alpha-amidating monooxygenase
  • Domestic Rabbit(100352005) peptidylglycine alpha-amidating monooxygenase
  • domestic guinea pig(100713254) peptidylglycine alpha-amidating monooxygenase
  • naked mole-rat(101716909) peptidylglycine alpha-amidating monooxygenase

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PAM antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-PAM/PAL antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-PAM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Pam,
Species
mouse
MISSION® esiRNA, targeting human PAM (1),
Species
human
MISSION® esiRNA, targeting human PAM (2),
Species
human
MISSION® esiRNA, targeting mouse Pam,
Species
mouse