RET
ret proto-oncogene
Synonyms:
CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1, RET51
Species:
Human RET (5979), Mouse Ret (19713), Rat Ret (24716), Zebrafish ret (30512), fruit fly ret (44319), fruit fly Ret (43875), chicken RET (396107), dog RET (403494), Horse RET (100033966), domestic cat RET (101101086) ...More
UniProtKB ID:
Gene ID:
- Human(5979) Summary: This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008]
- Mouse(19713) ret proto-oncogene
- Rat(24716) ret proto-oncogene
- Zebrafish(30512) ret proto-oncogene receptor tyrosine kinase
- fruit fly(44319) reticulated
- fruit fly(43875) Ret oncogene
- chicken(396107) ret proto-oncogene
- dog(403494) ret proto-oncogene
- Horse(100033966) ret proto-oncogene
- domestic cat(101101086) ret proto-oncogene
- cow(515924) ret proto-oncogene
- Domestic Rabbit(100340710) ret proto-oncogene
- sheep(101119787) ret proto-oncogene
- naked mole-rat(101717565) ret proto-oncogene
- domestic guinea pig(100733392) ret proto-oncogene
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Ret Antibody, clone 3U8T6, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-RET antibody produced in mouse, clone 1A5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
proximity ligation assay
western blot
proximity ligation assay
western blot
Monoclonal Anti-RET antibody produced in mouse, clone 6E4C4, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-RET antibody produced in mouse, clone 8D10C9, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-RET antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
Ret Protein, active, 10 µg, Active, N-Terminal GST-tagged, recombinant, human Ret amino acids 658-end, for use in Kinase Assays.,
Species
human
Ret (V804L) Protein, active, 10 µg, Active, N-Terminal GST-tagged, recombinant, human Ret amino acids 658 – end containing the V804L mutation. For use in Kinase Assays.,
Species
human
RET (V804L), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
Ret (V804M) Protein, active, 10 µg, Active, N-Terminal GST-tagged, recombinant, human Ret amino acids 658 – end containing the V804M mutation. For use in Kinase Assays.,
Species
human