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S1PR5

sphingosine-1-phosphate receptor 5

Synonyms:
EDG8, Edg-8, S1P5, SPPR-1, SPPR-2
Species:
UniProtKB ID:
Gene ID:
  • Human(53637) Summary: The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]
  • Mouse(94226) sphingosine-1-phosphate receptor 5
  • Rat(60399) sphingosine-1-phosphate receptor 5
  • domestic cat(101091512) sphingosine-1-phosphate receptor 5
  • dog(610828) sphingosine-1-phosphate receptor 5
  • cow(517533) sphingosine-1-phosphate receptor 5
  • sheep(101117761) sphingosine-1-phosphate receptor 5

Custom & Knockdown Gene Products

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Small Molecule - Antagonist

Product Number
Description
Species
SEW2871, ≥98% (HPLC), solid,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-EDG8 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry
Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1, clone 13F9.1, from mouse,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
Sphingosine 1-phosphate, ≥95%, powder,
Species
human
D-erythro-Dihydrosphingosine 1-phosphate, ≥98% (TLC), waxy solid,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse S1pr5,
Species
mouse
MISSION® esiRNA, targeting human S1PR5,
Species
human