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Merck

SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

Từ đồng nghĩa:
CERIII, CIAT, EIEE13, MED, NaCh6, Nav1.6, PN4
Loài:
ID UniProtKB:
ID gen:
  • Human(6334) Summary: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(20273) sodium channel, voltage-gated, type VIII, alpha
  • Rat(29710) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(100857835) sodium channel, voltage gated, type VIII, alpha subunit
  • dog(477604) sodium channel, voltage gated, type VIII, alpha subunit
  • Horse(100052777) sodium channel, voltage gated, type VIII, alpha subunit
  • cow(537277) sodium channel, voltage gated, type VIII, alpha subunit
  • naked mole-rat(101711868) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic guinea pig(100734003) sodium channel, voltage gated, type VIII, alpha subunit
  • sheep(101113744) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic cat(101096578) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(426869) sodium channel, voltage gated, type VIII, alpha subunit

Sản phẩm gen tùy chỉnh và tháo lắp

Antibodies

Số sản phẩm
Mô tả
Khả năng phản ứng theo loài
Ứng dụng
Monoclonal Anti-SCN8A antibody produced in mouse, clone 4G7, purified immunoglobulin, buffered aqueous solution,
Khả năng phản ứng theo loài
human, mouse, rat
Ứng dụng
ELISA
immunofluorescence

western blot
Anti-Sodium Channel PN4 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Khả năng phản ứng theo loài
rat
Ứng dụng
western blot
Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Khả năng phản ứng theo loài
mammals
Ứng dụng
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

Số sản phẩm
Mô tả
Loài
Carbamazepine, Pharmaceutical Secondary Standard; Certified Reference Material,
Loài
human
Lidocaine, Pharmaceutical Secondary Standard; Certified Reference Material,
Loài
human
Tetracaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Loài
human
Rufinamide, ≥98% (HPLC), powder,
Loài
human
Procaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Loài
human