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UHRF1

ubiquitin-like with PHD and ring finger domains 1

Synonyms:
ICBP90, Np95, RNF106, hNP95, hUHRF1
Species:
Human UHRF1 (29128), Mouse Uhrf1 (18140), Rat Uhrf1 (316129), chicken UHRF1 (420154), Zebrafish uhrf1 (406350), Zebrafish uhrf1 (100538017), naked mole-rat Uhrf1 (101719703), domestic guinea pig Uhrf1 (100719542), sheep UHRF1 (101113067), cow UHRF1 (530411) ...More
UniProtKB ID:
Q96T88, A0JBR2, A8K024, B2RBA9, Q2HIX7, Q8J022, Q9H6S6, Q9P115
Gene ID:
  • Human(29128) Summary: This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18140) ubiquitin-like, containing PHD and RING finger domains, 1
  • Rat(316129) ubiquitin-like with PHD and ring finger domains 1
  • chicken(420154) ubiquitin-like with PHD and ring finger domains 1
  • Zebrafish(406350) ubiquitin-like, containing PHD and RING finger domains, 1
  • Zebrafish(100538017) ubiquitin-like with PHD and ring finger domains 1
  • naked mole-rat(101719703) ubiquitin-like with PHD and ring finger domains 1
  • domestic guinea pig(100719542) ubiquitin-like with PHD and ring finger domains 1
  • sheep(101113067) ubiquitin-like with PHD and ring finger domains 1
  • cow(530411) ubiquitin-like with PHD and ring finger domains 1
  • Horse(100062347) ubiquitin-like with PHD and ring finger domains 1
  • domestic cat(101083658) ubiquitin-like with PHD and ring finger domains 1
  • dog(611463) ubiquitin-like with PHD and ring finger domains 1

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1405050
Monoclonal Anti-UHRF1 antibody produced in mouse, clone 3B12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
WH0029128M1
Monoclonal Anti-UHRF1 antibody produced in mouse, clone 3A11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
DR1047
Anti-UHRF1 Mouse mAb (3A11), liquid, clone 3A11, Calbiochem®,
Species Reactivity
human
Application
MABE945
Anti-E3 ubiquitin-protein ligase UHRF1 Antibody, clone 7C8, clone 7C8, 1 mg/mL, from mouse,
Species Reactivity
human
Application
ChIP
immunocytochemistry
western blot
MABE308
Anti-ICBP90/UHRF1 Antibody, clone 1RC1C-10, ascites fluid, clone 1RC-1C10, from mouse,
Species Reactivity
human
Application
ChIP
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EHU040501
MISSION® esiRNA, targeting human UHRF1,
Species
human
EMU030691
MISSION® esiRNA, targeting mouse Uhrf1,
Species
mouse