390062

Thiazol-Orange

Dye content ~90 %

• Synonym(e): 1-Methyl-4-[(3-methyl-2(3H)-benzothiazolyliden)-methyl]-chinolinium-p-tosylat
• Empirische Formel (Hill-System): C₂₆H₂₄N₂O₃S₂
• CAS-Nummer: 107091-89-4
• Molekulargewicht: 476.61
• NACRES: NA.47
• PubChem Substance ID: 24864313
• UNSPSC Code: 12171500
• MDL number: MFCD00192499

Eigenschaften

• form: powder
• Quality Segment: 200
• composition: Dye content, ~90%
• technique(s): titration: suitable
• mp: 270 °C (dec.) (lit.)
• λmax: 512 nm
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: Cc1ccc(cc1)S([O-])(=O)=O.CN2C(\Sc3ccccc23)=C\c4cc[n+](C)c5ccccc45
• InChI: 1S/C19H17N2S.C7H8O3S/c1-20-12-11-14(15-7-3-4-8-16(15)20)13-19-21(2)17-9-5-6-10-18(17)22-19;1-6-2-4-7(5-3-6)11(8,9)10/h3-13H,1-2H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
• InChI key: ACOJCCLIDPZYJC-UHFFFAOYSA-M

Beschreibung

General description

Thiazole Orange can be tethered with peptide nucleic acid for the detection of target nucleic acid in homogeneous solution. It is a dye with, both predicted physical characteristics and the biological staining characteristics of a good reticulocyte dye, hence it is considered as a dye for reticulocyte analysis. It has massive fluorescence enhancement and high quantum yield upon binding to nucleic acids, particularly RNA. It is non precipitating and can permeates through live cell membranes.

Application

Thiazole orange has been used for the staining and thereby quantification of reticulocytes.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H315,H319,H335
• Sicherheitshinweise: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Gloves