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135496

Sigma-Aldrich

3-Amino-L-tyrosine dihydrochloride monohydrate

98%

Synonym(s):

3-Amino-L-tyrosine dihydrochloride

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About This Item

Linear Formula:
H2NC6H3-4-(OH)CH2CH(NH2)CO2H · 2HCl · H2O
CAS Number:
23279-22-3
Molecular Weight:
287.14
EC Number:
245-552-5
MDL number:
MFCD00150105
UNSPSC Code:
12352209
PubChem Substance ID:
24848207
NACRES:
NA.22

Assay

98%

optical activity

[α]22/D −1.6°, c = 2 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

158-160 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

O.Cl.Cl.N[C@@H](Cc1ccc(O)c(N)c1)C(O)=O

InChI

1S/C9H12N2O3.2ClH.H2O/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14;;;/h1-3,7,12H,4,10-11H2,(H,13,14);2*1H;1H2/t7-;;;/m0.../s1

InChI key

ITQBVYBSXFBTJX-QTPLPEIMSA-N

General description

3-Amino-L-tyrosine dihydrochloride monohydrate also known as 3-Amino-L-tyrosine dihydrochloride, is commonly used in the solution-phase peptide synthesis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Katrin M Hinz et al.
Molecular endocrinology (Baltimore, Md.), 29(6), 933-942 (2015-05-07)
Thyroid hormones (THs) are transported across cell membranes by different transmembrane transporter proteins. In previous studies, we showed marked 3,3'-diiodothyronine (3,3'-T2) but moderate T3 uptake by the L-type amino acid transporter 2 (Lat2). We have now studied the structure-function relationships

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