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608130

Sigma-Aldrich

L-Serine-13C3,15N

98 atom % 15N, 98 atom % 13C, 95% (CP)

Synonym(s):

L-Serine-UL-13C,15N

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About This Item

Linear Formula:
HO13CH213CH(15NH2)13CO2H
CAS Number:
202407-34-9
Molecular Weight:
109.06
MDL number:
MFCD00144678
UNSPSC Code:
12352209
PubChem Substance ID:
329759233
NACRES:
NA.12

isotopic purity

98 atom % 13C
98 atom % 15N

Assay

95% (CP)

form

solid

optical activity

[α]25/D +14.6°, c = 2 in 1 M HCl

technique(s)

bio NMR: suitable

mp

222 °C (dec.) (lit.)

mass shift

M+4

SMILES string

[15NH2][13C@@H]([13CH2]O)[13C](O)=O

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1/i1+1,2+1,3+1,4+1

InChI key

MTCFGRXMJLQNBG-UVYXLFMMSA-N

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Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

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Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Marc Hennequart et al.
Nature communications, 12(1), 6176-6176 (2021-10-28)
Serine is a non-essential amino acid that is critical for tumour proliferation and depletion of circulating serine results in reduced tumour growth and increased survival in various cancer models. While many cancer cells cultured in a standard tissue culture medium
Dominic G Roy et al.
Cell metabolism, 31(2), 250-266 (2020-02-06)
Epigenetic modifications on DNA and histones regulate gene expression by modulating chromatin accessibility to transcription machinery. Here we identify methionine as a key nutrient affecting epigenetic reprogramming in CD4+ T helper (Th) cells. Using metabolomics, we showed that methionine is

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