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900398

Sigma-Aldrich

SnAP-ex 3-N-Boc P Reagent

95%

Synonym(s):

tert-Butyl (4-amino-1-(tributylstannyl)butyl)carbamate

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About This Item

Empirical Formula (Hill Notation):
C21H46N2O2Sn
Molecular Weight:
477.31
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

95%

form

paste

refractive index

n/D 1.4963

density

1.1316 g/mL

storage temp.

−20°C

Application

SnAP reagents provide a one-step route, in tandem with various aldehyde substrates, to saturated N-heterocycles. The synthesis of N-heterocycles through SnAP reagents requires mild reaction conditions, and aldehydes bearing aryl, heteroaryl, glyoxyl, aliphatic, and halogenated groups are well tolerated. This product was introduced in collaboration with the Bode research group.

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Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3


Certificates of Analysis (COA)

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SnAP-eX reagents for the synthesis of exocyclic 3-amino-and 3-alkoxypyrrolidines and piperidines from aldehydes.
Luescher M U and Bode J W
Organic Letters, 18(11), 2652-2655 (2016)

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