Skip to Content
MilliporeSigma
All Photos(1)

Documents

900889

Sigma-Aldrich

Lithium phenyl-2,4,6-trimethylbenzoylphosphinate

≥95%

Synonym(s):

LAP

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C16H16LiO3P
CAS Number:
Molecular Weight:
294.21
UNSPSC Code:
12352128
NACRES:
NA.23

Quality Level

Assay

≥95%

form

crystalline powder

color

white to off-white

storage temp.

2-8°C

SMILES string

CC1=C(C(P(C2=CC=CC=C2)(O[Li])=O)=O)C(C)=CC(C)=C1

Looking for similar products? Visit Product Comparison Guide

Application

Lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) is a water soluble, cytocompatible, Type I photoinitiator for use in the polymerization of hydrogels or other polymeric materials. This photoinitator is preferred over Irgacure 2959 for biological applications due to its increased water solubility, increased polymerization rates with 365 nm light, and absorbance at 400 nm allowing for polymerization with visible light. The improved polymerization kinetics enable cell encapsualation at reduced initiator concentration and longer wavelength light, which has been shown to reduce initiator toxicity and increase cell viability.

Features and Benefits

  • Superior water solubility
  • Biocompatible
  • Sensitiveto visible light

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Tiffany Zhang et al.
Scientific reports, 10(1), 15796-15796 (2020-09-27)
Inspired by the interesting natural antimicrobial properties of honey, biohybrid composite materials containing a low-fouling polymer hydrogel network and an encapsulated antimicrobial peroxide-producing enzyme have been developed. These synergistically combine both passive and active mechanisms for reducing microbial bacterial colonization.
Joshua D McCall et al.
Biomacromolecules, 13(8), 2410-2417 (2012-06-30)
Photoinitiated polymerization remains a robust method for fabrication of hydrogels, as these reactions allow facile spatial and temporal control of gelation and high compatibility for encapsulation of cells and biologics. The chain-growth reaction of macromolecular monomers, such as acrylated PEG
Zhiguang Qiao et al.
Biomaterials, 266, 120385-120385 (2020-10-30)
Despite significant advances in osteochondral tissue engineering, it remains challenging to successfully reconstruct native-like complex tissues organized in three-dimension with spatially varying compositional, structural and functional properties. In this contribution, inspired by the gradients in extracellular matrix (ECM) composition and
Benjamin D Fairbanks et al.
Macromolecules, 44(8), 2444-2450 (2011-04-23)
Various techniques have been adopted to impart a biological responsiveness to synthetic hydrogels for the delivery of therapeutic agents as well as the study and manipulation of biological processes and tissue development. Such techniques and materials include polyelectrolyte gels that
Benjamin D Fairbanks et al.
Biomaterials, 30(35), 6702-6707 (2009-09-29)
Due to mild reaction conditions and temporal and spatial control over material formation, photopolymerization has become a valuable technique for the encapsulation of living cells in three dimensional, hydrated, biomimetic materials. For such applications, 2-hydroxy-1-[4-(2-hydroxyethoxy) phenyl]-2-methyl-1-propanone (I2959) is the most

Articles

Water-dispersible photoinitiator nanoparticles enable novel formulations for 3D bioprinting, tissue engineering, and device manufacturing.

Related Content

Tissue engineering fabricates tissues cultures from scaffolds, living cells, and biologically active molecules by simulating the microenvironment of the body to repair or replace damaged tissue.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service